Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA17_RS21565 Genome accession   NZ_CP108115
Coordinates   4689746..4690414 (+) Length   222 a.a.
NCBI ID   WP_053726427.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00212     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4684746..4695414
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA17_RS21540 (OHA17_21470) - 4684871..4685740 (+) 870 WP_406507948.1 alpha/beta hydrolase -
  OHA17_RS21545 (OHA17_21475) - 4685919..4687085 (-) 1167 WP_406507949.1 GDSL-type esterase/lipase family protein -
  OHA17_RS21550 (OHA17_21480) - 4687082..4687651 (-) 570 WP_398874787.1 TetR/AcrR family transcriptional regulator -
  OHA17_RS21555 (OHA17_21485) - 4687773..4688267 (+) 495 WP_406507950.1 FBP domain-containing protein -
  OHA17_RS21560 (OHA17_21490) - 4688370..4689749 (+) 1380 WP_406507951.1 sensor histidine kinase -
  OHA17_RS21565 (OHA17_21495) vraR 4689746..4690414 (+) 669 WP_053726427.1 response regulator transcription factor Regulator
  OHA17_RS21570 (OHA17_21500) - 4690909..4692138 (+) 1230 WP_406507952.1 cytochrome P450 -
  OHA17_RS21575 (OHA17_21505) - 4692149..4693756 (-) 1608 WP_406507953.1 ABC transporter permease -
  OHA17_RS21580 (OHA17_21510) - 4693753..4694661 (-) 909 WP_406507954.1 ATP-binding cassette domain-containing protein -
  OHA17_RS21585 (OHA17_21515) - 4694763..4695302 (+) 540 WP_053724763.1 GbsR/MarR family transcriptional regulator -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 24026.63 Da        Isoelectric Point: 4.6426

>NTDB_id=654025 OHA17_RS21565 WP_053726427.1 4689746..4690414(+) (vraR) [Streptomyces sp. NBC_00212]
MTIKVLIVDDQMMVREGFSVLLGAQPDIEVVGEAVDGREAVAQVRTLRPDVVLMDIRMPGMNGIEATREIVASDDSSKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLAEGVRVVASGEALLAPSVTRRLINEFARVVPVQRAGSSAPPGQVEELT
DRETEVLVLIAQGLSNQEIADRLVVAESTIKTHVSRVLVKLGLRDRTQAAVYAYETRLVTPG

Nucleotide


Download         Length: 669 bp        

>NTDB_id=654025 OHA17_RS21565 WP_053726427.1 4689746..4690414(+) (vraR) [Streptomyces sp. NBC_00212]
ATGACGATCAAGGTCCTGATCGTCGACGACCAGATGATGGTGCGCGAGGGCTTCTCCGTACTGCTCGGCGCGCAGCCGGA
CATCGAGGTCGTCGGCGAGGCGGTCGACGGCCGCGAGGCGGTCGCCCAGGTGCGGACGCTGCGTCCCGACGTGGTCCTGA
TGGACATCCGGATGCCCGGCATGAACGGCATCGAGGCGACGCGGGAGATCGTGGCGTCGGACGACTCCTCGAAGGTGCTC
GTCCTGACCACGTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGGGCGGGGGCGTCGGGCTTCCTCCTGAAGGACGC
GTCGGCGCGTCAACTAGCCGAGGGCGTACGGGTGGTGGCGTCCGGGGAGGCGCTGCTCGCCCCCTCGGTGACCCGGCGGC
TGATCAACGAGTTCGCGCGGGTCGTGCCGGTGCAGCGGGCGGGTTCCTCCGCGCCGCCCGGCCAGGTGGAGGAGCTGACC
GACCGCGAGACGGAGGTGCTCGTCCTGATCGCCCAGGGTCTGTCGAACCAGGAGATCGCGGACCGCCTTGTCGTGGCGGA
GTCGACGATCAAGACCCATGTGAGCCGGGTCCTGGTGAAGCTGGGGCTGCGGGACCGGACGCAGGCGGCGGTATACGCGT
ACGAAACCCGCCTGGTAACCCCGGGTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(159-213)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.205

98.649

0.446
  degU Bacillus subtilis subsp. subtilis str. 168

42.92

100

0.437