Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA17_RS18260 Genome accession   NZ_CP108115
Coordinates   4002560..4003186 (+) Length   208 a.a.
NCBI ID   WP_053728166.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00212     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3997560..4008186
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA17_RS18240 (OHA17_18175) - 3997575..3999077 (+) 1503 WP_406510753.1 M4 family metallopeptidase -
  OHA17_RS18245 (OHA17_18180) - 3999111..4000571 (-) 1461 WP_406507497.1 M1 family metallopeptidase -
  OHA17_RS18250 (OHA17_18185) - 4000602..4001147 (-) 546 WP_406507498.1 heme-binding protein -
  OHA17_RS18255 (OHA17_18190) - 4001313..4002563 (+) 1251 WP_406507499.1 sensor histidine kinase -
  OHA17_RS18260 (OHA17_18195) vraR 4002560..4003186 (+) 627 WP_053728166.1 response regulator transcription factor Regulator
  OHA17_RS18265 (OHA17_18200) - 4003781..4004281 (+) 501 WP_406507500.1 hypothetical protein -
  OHA17_RS18270 (OHA17_18205) - 4004362..4005045 (-) 684 WP_234392206.1 pentapeptide repeat-containing protein -
  OHA17_RS18275 (OHA17_18210) - 4005198..4006409 (+) 1212 WP_406507501.1 NAD(P)-binding protein -
  OHA17_RS18280 (OHA17_18215) - 4006564..4007316 (+) 753 WP_406507502.1 DUF6879 family protein -
  OHA17_RS18285 (OHA17_18220) - 4007313..4008155 (+) 843 WP_406507503.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 208 a.a.        Molecular weight: 21877.17 Da        Isoelectric Point: 5.7646

>NTDB_id=654015 OHA17_RS18260 WP_053728166.1 4002560..4003186(+) (vraR) [Streptomyces sp. NBC_00212]
MTDPVRILLCDDHAVVRAGLLALIGSEPDIEVAGEAGSGEEAVAAAAKLKPDVVLMDLQLGPGIDGVEATRRISATGVHV
LVLTTYDTDADITRAIAAGATGYLLKAERPEELFAAIRAAAEGRTTLSPPVASRVMNQLRGASRPTLTPRELDILAQLAN
GLGNREIARALFISEATVKTHLGRIYDKLGVETRAGAVSVAKERRLLP

Nucleotide


Download         Length: 627 bp        

>NTDB_id=654015 OHA17_RS18260 WP_053728166.1 4002560..4003186(+) (vraR) [Streptomyces sp. NBC_00212]
ATGACCGACCCCGTACGGATTCTGCTCTGCGACGACCACGCGGTGGTGCGCGCGGGGCTGCTCGCGCTCATCGGCAGCGA
GCCGGACATCGAGGTGGCCGGGGAGGCCGGCAGCGGCGAGGAGGCGGTGGCCGCGGCGGCCAAGCTGAAGCCGGACGTAG
TACTGATGGACCTCCAGCTGGGCCCCGGCATCGACGGCGTGGAGGCCACCCGGCGCATCTCCGCGACCGGGGTGCACGTC
CTGGTCCTCACCACCTACGACACGGACGCCGACATCACGCGGGCGATCGCGGCGGGCGCGACCGGCTACCTCCTCAAAGC
CGAACGCCCCGAGGAGCTCTTCGCCGCGATCCGGGCGGCCGCCGAGGGCCGCACCACGCTGTCCCCGCCGGTGGCCAGCC
GCGTCATGAACCAGCTCCGCGGCGCCTCCCGCCCCACCCTCACACCCCGCGAACTCGACATCCTGGCCCAGCTGGCGAAC
GGCCTGGGCAACCGGGAAATCGCCCGCGCGCTGTTCATCAGCGAGGCGACGGTGAAGACCCATCTGGGCCGGATCTACGA
CAAGCTCGGGGTCGAGACGCGGGCGGGGGCGGTTTCCGTGGCCAAGGAGCGGCGGCTTCTGCCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(146-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.423

100

0.394
  degU Bacillus subtilis subsp. subtilis str. 168

37.156

100

0.389