Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA17_RS08325 Genome accession   NZ_CP108115
Coordinates   1814236..1814907 (-) Length   223 a.a.
NCBI ID   WP_406505420.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00212     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1809236..1819907
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA17_RS08295 (OHA17_08240) - 1809644..1810555 (-) 912 WP_406505410.1 LysR family transcriptional regulator -
  OHA17_RS08300 (OHA17_08245) - 1810879..1811814 (+) 936 WP_406505412.1 NADP-dependent oxidoreductase -
  OHA17_RS08305 (OHA17_08250) - 1811853..1812470 (+) 618 WP_406505414.1 Type 1 glutamine amidotransferase-like domain-containing protein -
  OHA17_RS08310 (OHA17_08255) - 1812516..1812983 (+) 468 WP_406505416.1 carboxymuconolactone decarboxylase family protein -
  OHA17_RS08315 - 1813170..1813418 (+) 249 Protein_1654 NmrA family NAD(P)-binding protein -
  OHA17_RS08320 (OHA17_08260) - 1813495..1814097 (+) 603 WP_406505418.1 NAD-dependent epimerase/dehydratase family protein -
  OHA17_RS08325 (OHA17_08265) vraR 1814236..1814907 (-) 672 WP_406505420.1 response regulator Regulator
  OHA17_RS08330 (OHA17_08270) - 1814904..1816079 (-) 1176 WP_406505422.1 sensor histidine kinase -
  OHA17_RS08335 (OHA17_08275) - 1816289..1817209 (+) 921 WP_406505424.1 ABC transporter ATP-binding protein -
  OHA17_RS08340 (OHA17_08280) - 1817206..1818039 (+) 834 WP_406505426.1 ABC transporter permease -
  OHA17_RS08345 (OHA17_08285) - 1818219..1818446 (+) 228 WP_406505428.1 hypothetical protein -
  OHA17_RS08350 (OHA17_08290) - 1818555..1818761 (-) 207 WP_406505430.1 hypothetical protein -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 23768.52 Da        Isoelectric Point: 4.8333

>NTDB_id=653978 OHA17_RS08325 WP_406505420.1 1814236..1814907(-) (vraR) [Streptomyces sp. NBC_00212]
MTGGPVRVLLVDDQPLVRSGLRVIMADHPDLEVVGEASTGAEAVQLVGEICPDVVVMDIRMPGMDGIEATRLITAGPATT
RVLVLTTFDEDDHVYGALRAGASGFMVKDMALDDILAAIRVVAAGDALIAPGVTRRLIAEFAGRPEAAPAPSPRLVEGIT
EREREVLTLVGRGRSNTEIAEDLFITVATAKSHVSRLLTKLGARDRVQLVITAYETRLVTLPR

Nucleotide


Download         Length: 672 bp        

>NTDB_id=653978 OHA17_RS08325 WP_406505420.1 1814236..1814907(-) (vraR) [Streptomyces sp. NBC_00212]
ATGACCGGCGGTCCCGTACGCGTCCTGCTCGTCGACGACCAGCCGCTGGTGCGGTCCGGCCTGCGCGTGATCATGGCCGA
CCACCCCGACCTGGAAGTCGTCGGTGAGGCGTCCACCGGCGCCGAGGCGGTCCAGCTGGTGGGGGAAATATGCCCCGACG
TCGTGGTGATGGACATCCGGATGCCCGGCATGGACGGGATCGAGGCCACCCGCCTGATCACCGCCGGGCCGGCGACCACC
CGCGTCCTCGTCCTGACCACCTTCGACGAGGACGACCACGTCTACGGCGCGCTCCGGGCCGGCGCGAGCGGCTTCATGGT
CAAGGACATGGCGCTCGACGACATCCTCGCGGCGATCCGCGTGGTCGCCGCCGGCGACGCGCTGATCGCCCCGGGCGTCA
CGCGCCGTCTGATCGCAGAGTTCGCCGGGCGCCCCGAAGCCGCCCCGGCACCCTCCCCACGACTGGTCGAGGGCATCACC
GAGCGGGAACGGGAAGTCCTGACCCTGGTCGGACGCGGCCGGTCGAACACCGAGATCGCCGAGGACCTCTTCATCACGGT
GGCCACCGCCAAGTCGCACGTCTCTCGCCTGCTCACCAAACTGGGCGCCCGGGACCGCGTCCAGCTCGTCATCACCGCCT
ACGAGACGAGGCTCGTCACGCTGCCTCGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(8-120)

Bacterial regulatory proteins, luxR family (GerE)

(159-213)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.72

95.964

0.381
  degU Bacillus subtilis subsp. subtilis str. 168

36.444

100

0.368