Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG965_RS19810 Genome accession   NZ_CP108106
Coordinates   4486144..4486758 (+) Length   204 a.a.
NCBI ID   WP_371653421.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00224     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4481144..4491758
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG965_RS19795 (OG965_19745) - 4482624..4484021 (-) 1398 WP_371653419.1 M1 family metallopeptidase -
  OG965_RS19800 (OG965_19750) - 4484119..4484694 (-) 576 WP_371653420.1 heme-binding protein -
  OG965_RS19805 (OG965_19755) - 4484984..4486147 (+) 1164 WP_371656997.1 sensor histidine kinase -
  OG965_RS19810 (OG965_19760) vraR 4486144..4486758 (+) 615 WP_371653421.1 response regulator Regulator
  OG965_RS19815 (OG965_19765) - 4487160..4487663 (+) 504 WP_371656998.1 hypothetical protein -
  OG965_RS19820 (OG965_19770) - 4487726..4488394 (-) 669 WP_371653422.1 pentapeptide repeat-containing protein -
  OG965_RS19825 (OG965_19775) - 4488506..4489663 (+) 1158 WP_371653423.1 FAD-dependent oxidoreductase -
  OG965_RS19830 (OG965_19780) - 4489748..4490755 (+) 1008 WP_371653424.1 zinc-binding dehydrogenase -
  OG965_RS19835 (OG965_19785) - 4490776..4491624 (-) 849 WP_371653425.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 204 a.a.        Molecular weight: 21587.90 Da        Isoelectric Point: 6.4964

>NTDB_id=653855 OG965_RS19810 WP_371653421.1 4486144..4486758(+) (vraR) [Streptomyces sp. NBC_00224]
MKVLLCDDHAVVRAGLLALLGSEPDIEVVGEAGTGEEAVAAAAKVRPDVVLMDLQLGPGIDGVEATRRIAGTGVRVLVLT
TYDTDADITRAIAAGATGYLLKAERPEELFAAIRAAAQGRTALSPPVASRVMERMRGTGRPTLTDRELDILAQLSRGLGN
REIARALFISEATVKTHLGRIYEKLGVETRAGAVAEGKERRLLP

Nucleotide


Download         Length: 615 bp        

>NTDB_id=653855 OG965_RS19810 WP_371653421.1 4486144..4486758(+) (vraR) [Streptomyces sp. NBC_00224]
ATGAAGGTGCTGTTGTGCGACGACCACGCGGTCGTACGGGCCGGACTGCTCGCGCTGCTCGGCAGCGAGCCCGACATCGA
GGTGGTCGGGGAGGCGGGCACCGGCGAGGAGGCGGTCGCGGCGGCGGCCAAGGTACGGCCCGACGTCGTGCTGATGGACC
TCCAGCTCGGCCCGGGCATCGACGGGGTCGAGGCGACCCGGCGGATCGCGGGGACGGGGGTGCGGGTGCTCGTCCTGACC
ACGTACGACACGGACGCGGACATCACACGGGCGATCGCCGCCGGAGCGACGGGGTACCTGCTGAAGGCCGAGCGCCCGGA
GGAACTCTTCGCGGCGATCCGCGCGGCCGCCCAGGGCCGCACCGCCCTGTCGCCCCCCGTGGCGAGCCGCGTCATGGAAC
GCATGCGGGGCACCGGCCGCCCCACGCTCACCGACCGCGAACTGGACATCCTGGCGCAGCTCTCCCGCGGCCTGGGCAAC
CGCGAGATCGCACGGGCGCTGTTCATCAGCGAGGCGACGGTGAAGACGCATCTGGGCCGGATCTACGAGAAGTTGGGGGT
GGAGACGCGGGCGGGGGCGGTGGCGGAGGGGAAGGAGCGCCGCCTGCTCCCGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(142-194)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.614

100

0.402
  degU Bacillus subtilis subsp. subtilis str. 168

34.419

100

0.363