Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG965_RS11650 Genome accession   NZ_CP108106
Coordinates   2612500..2613141 (-) Length   213 a.a.
NCBI ID   WP_371651825.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00224     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2607500..2618141
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG965_RS11620 (OG965_11575) - 2607665..2608441 (-) 777 WP_371651815.1 sulfite exporter TauE/SafE family protein -
  OG965_RS11625 (OG965_11580) - 2608535..2609464 (-) 930 WP_067157382.1 SPFH domain-containing protein -
  OG965_RS11630 (OG965_11585) - 2609544..2609966 (-) 423 WP_371651817.1 NfeD family protein -
  OG965_RS11635 (OG965_11590) - 2610026..2610817 (-) 792 WP_371651819.1 ABC transporter ATP-binding protein -
  OG965_RS11640 (OG965_11595) - 2610956..2611753 (+) 798 WP_371651821.1 hypothetical protein -
  OG965_RS11645 (OG965_11600) - 2612086..2612328 (-) 243 WP_371651823.1 chaplin -
  OG965_RS11650 (OG965_11605) vraR 2612500..2613141 (-) 642 WP_371651825.1 response regulator Regulator
  OG965_RS11655 (OG965_11610) - 2613134..2614279 (-) 1146 WP_371651827.1 GAF domain-containing sensor histidine kinase -
  OG965_RS11660 (OG965_11615) - 2614502..2615200 (+) 699 WP_371651829.1 SDR family NAD(P)-dependent oxidoreductase -
  OG965_RS11665 (OG965_11620) - 2615229..2616365 (+) 1137 WP_371651831.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OG965_RS11670 (OG965_11625) - 2616634..2617299 (+) 666 WP_371651833.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22828.15 Da        Isoelectric Point: 5.3661

>NTDB_id=653836 OG965_RS11650 WP_371651825.1 2612500..2613141(-) (vraR) [Streptomyces sp. NBC_00224]
MADSIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVARAEELKPDVVLMDVKMPGMDGIEALRKLRTLANPAK
VLIVTSFTEQRTVVPALRAGAAGYVYKDVDPEALAGAIRSVHAGHVLLQPEVAGALLSQDDAGGGQGRGTSLTEREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGLTD

Nucleotide


Download         Length: 642 bp        

>NTDB_id=653836 OG965_RS11650 WP_371651825.1 2612500..2613141(-) (vraR) [Streptomyces sp. NBC_00224]
GTGGCTGACAGCATCAAAGTCCTCCTGGTCGACGACCACCAGGTGGTCCGCCGCGGCCTGCGGACGTTCCTGGAGGTCCA
GGACGACATAGAGGTCGTCGGCGAGGCCGCCGACGGGGCCGAGGGGGTCGCCCGAGCCGAGGAGCTGAAGCCGGACGTCG
TCCTGATGGACGTGAAGATGCCCGGCATGGACGGCATCGAGGCGCTGCGCAAGCTGCGCACGCTGGCCAACCCGGCGAAG
GTGCTGATCGTCACCAGCTTCACCGAGCAGCGCACGGTGGTGCCCGCGCTGCGGGCGGGCGCGGCGGGCTATGTGTACAA
GGACGTCGACCCGGAGGCACTGGCCGGCGCGATCCGCTCGGTGCACGCCGGGCACGTGCTGCTCCAGCCCGAGGTCGCGG
GCGCACTGCTCTCCCAGGACGACGCGGGCGGCGGCCAGGGCCGGGGCACCTCGCTCACCGAGCGCGAGCGCGAAGTCCTT
GGCCTGATCGCGGACGGCCGCTCGAACCGGGAGATCGCCCGAGCACTGGTCCTGTCCGAGAAGACGGTGAAAACACACGT
CTCCAACATCCTGATGAAGCTGGACCTGGCGGACCGCACCCAGGCGGCCCTGTGGGCGGTCCGCCACGGCCTGACGGACT
GA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

47.115

97.653

0.46
  degU Bacillus subtilis subsp. subtilis str. 168

37.5

100

0.394