Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG965_RS08765 Genome accession   NZ_CP108106
Coordinates   1967144..1967794 (+) Length   216 a.a.
NCBI ID   WP_190091369.1    Uniprot ID   A0ABV6TV33
Organism   Streptomyces sp. NBC_00224     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1962144..1972794
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG965_RS08735 (OG965_08690) - 1962382..1962966 (-) 585 WP_371650875.1 hypothetical protein -
  OG965_RS08740 (OG965_08695) - 1963113..1963514 (-) 402 WP_371650877.1 hypothetical protein -
  OG965_RS08745 (OG965_08700) - 1963621..1964058 (-) 438 WP_371650879.1 hypothetical protein -
  OG965_RS08750 (OG965_08705) - 1964096..1964842 (-) 747 WP_371650881.1 ABC transporter permease -
  OG965_RS08755 (OG965_08710) - 1964846..1965859 (-) 1014 WP_371650883.1 ABC transporter ATP-binding protein -
  OG965_RS08760 (OG965_08715) - 1965967..1967139 (+) 1173 WP_371650885.1 sensor histidine kinase -
  OG965_RS08765 (OG965_08720) vraR 1967144..1967794 (+) 651 WP_190091369.1 response regulator transcription factor Regulator
  OG965_RS08770 (OG965_08725) - 1967883..1969040 (+) 1158 WP_371650887.1 ROK family transcriptional regulator -
  OG965_RS08775 (OG965_08730) - 1969320..1970081 (-) 762 WP_371650889.1 GntR family transcriptional regulator -
  OG965_RS08780 (OG965_08735) sigJ 1970332..1971240 (-) 909 WP_371650891.1 RNA polymerase sigma factor SigJ -
  OG965_RS08785 (OG965_08740) - 1971427..1972257 (+) 831 WP_371650893.1 alpha/beta fold hydrolase -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23078.74 Da        Isoelectric Point: 5.1543

>NTDB_id=653830 OG965_RS08765 WP_190091369.1 1967144..1967794(+) (vraR) [Streptomyces sp. NBC_00224]
MPVTVLLVDDEPLVRAGLRAVLEAQPDIEVVGEAADGAAVIPLVRRLRPDVVAMDVRMPLLDGIEATRAVLRTVQDPPKI
LVVTTFENDEYVYEALRAGADGFLLKRARPAEIVHAVRLVAEGESLLFPAAVRSLAAEYGNRDARAALDKAALTEREAAV
LRLMARGLSNAEIAARLIVGTETVKTHVSAVLAKLGARDRTQAVIAAYESGFVAPS

Nucleotide


Download         Length: 651 bp        

>NTDB_id=653830 OG965_RS08765 WP_190091369.1 1967144..1967794(+) (vraR) [Streptomyces sp. NBC_00224]
ATGCCGGTTACCGTTCTTCTCGTCGACGACGAACCCCTGGTCCGTGCGGGTCTGCGTGCCGTACTGGAGGCCCAGCCCGA
CATCGAGGTGGTGGGTGAGGCCGCCGATGGCGCCGCCGTCATCCCGCTGGTGCGCCGGCTGCGCCCCGATGTGGTGGCGA
TGGATGTCCGGATGCCGTTGCTCGACGGGATAGAGGCCACTCGGGCGGTGCTGCGCACGGTGCAGGATCCGCCGAAGATC
TTGGTGGTCACAACGTTCGAGAACGACGAGTACGTGTACGAGGCTCTACGGGCCGGTGCCGATGGGTTTCTGCTGAAGCG
GGCCCGGCCCGCCGAGATCGTGCACGCGGTGCGGCTCGTCGCGGAGGGCGAATCGCTGCTGTTCCCGGCGGCGGTCCGTT
CGCTCGCGGCCGAGTACGGCAACCGGGACGCACGGGCGGCGCTGGACAAGGCGGCACTCACCGAGCGGGAGGCGGCCGTT
CTGCGGCTGATGGCGCGCGGGCTCTCCAACGCGGAGATCGCCGCCCGGCTGATCGTCGGCACCGAGACGGTGAAGACGCA
TGTCAGCGCCGTCCTGGCCAAGTTGGGCGCCCGGGACCGGACCCAGGCGGTGATCGCGGCGTACGAGTCGGGATTCGTGG
CTCCGAGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-118)

Bacterial regulatory proteins, luxR family (GerE)

(152-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.326

99.537

0.421
  degU Bacillus subtilis subsp. subtilis str. 168

35.556

100

0.37