Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG537_RS23195 Genome accession   NZ_CP108102
Coordinates   5279465..5280133 (+) Length   222 a.a.
NCBI ID   WP_328933462.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00228     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5274465..5285133
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG537_RS23175 (OG537_23155) kynU 5274920..5276119 (+) 1200 WP_328933459.1 kynureninase -
  OG537_RS23180 (OG537_23160) - 5276126..5276806 (-) 681 WP_328933460.1 TetR/AcrR family transcriptional regulator -
  OG537_RS23185 (OG537_23165) - 5277068..5278000 (+) 933 WP_328933461.1 alpha/beta hydrolase -
  OG537_RS23190 (OG537_23170) - 5278143..5279468 (+) 1326 WP_328936125.1 histidine kinase -
  OG537_RS23195 (OG537_23175) vraR 5279465..5280133 (+) 669 WP_328933462.1 response regulator transcription factor Regulator
  OG537_RS23200 (OG537_23180) - 5280249..5281472 (+) 1224 WP_328933463.1 cytochrome P450 -
  OG537_RS23205 (OG537_23185) - 5281504..5282058 (-) 555 WP_328933464.1 MarR family transcriptional regulator -
  OG537_RS23210 (OG537_23190) - 5282140..5283600 (+) 1461 WP_328933465.1 MFS transporter -
  OG537_RS23215 (OG537_23195) - 5283678..5284169 (-) 492 WP_328830619.1 hypothetical protein -
  OG537_RS23220 (OG537_23200) - 5284222..5284905 (-) 684 WP_328830620.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 23929.66 Da        Isoelectric Point: 4.6681

>NTDB_id=653771 OG537_RS23195 WP_328933462.1 5279465..5280133(+) (vraR) [Streptomyces sp. NBC_00228]
MTIRVLIADDQMMVREGFSVLLGAMPDIEVVGEAVNGRDAVERVRELAPDVVLMDIRMPELNGIEATREIVAADGAAKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVAAGEALLAPSVTRRLITEFSKLADSPRVMPAAAQGTYGELT
ERETEVLVLIAQGLSNGEIAERLVVAESTIKTHVSRVLVKLGLRDRTQAAVFAYEARLVRPG

Nucleotide


Download         Length: 669 bp        

>NTDB_id=653771 OG537_RS23195 WP_328933462.1 5279465..5280133(+) (vraR) [Streptomyces sp. NBC_00228]
ATGACCATCCGCGTGCTGATCGCGGACGACCAGATGATGGTGCGCGAGGGCTTCTCGGTCCTGTTGGGCGCGATGCCGGA
CATCGAGGTGGTCGGCGAGGCGGTGAACGGACGCGACGCGGTGGAGCGCGTACGCGAACTGGCCCCGGACGTGGTCCTGA
TGGACATCCGCATGCCGGAGCTGAACGGCATCGAGGCGACCAGGGAGATCGTCGCGGCGGACGGCGCGGCGAAGGTGCTG
GTGCTGACCACGTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGGGCGGGCGCCTCCGGCTTCCTCCTCAAGGACGC
CTCGGCACGTCAACTGGCCGACGGGGTGAGGGTGGTGGCGGCAGGCGAGGCCCTGCTCGCCCCCTCCGTCACCAGACGGC
TGATCACGGAGTTCTCGAAGCTGGCCGACTCGCCCCGCGTGATGCCGGCCGCGGCGCAGGGGACGTACGGGGAGCTGACC
GAGCGGGAGACGGAGGTGCTGGTCCTCATCGCGCAGGGGTTGTCGAACGGGGAGATCGCCGAGCGGCTGGTGGTCGCCGA
GTCGACGATCAAGACCCACGTCAGCCGCGTCCTGGTGAAGCTGGGCCTCCGGGACCGGACCCAGGCGGCGGTGTTCGCGT
ACGAGGCGAGGCTGGTGAGGCCGGGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(159-213)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.182

99.099

0.428
  degU Bacillus subtilis subsp. subtilis str. 168

42.661

98.198

0.419