Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG537_RS20565 Genome accession   NZ_CP108102
Coordinates   4737471..4738163 (-) Length   230 a.a.
NCBI ID   WP_328933186.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00228     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4732471..4743163
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG537_RS20535 (OG537_20510) - 4733610..4733945 (-) 336 WP_328830228.1 MerR family transcriptional regulator -
  OG537_RS20540 (OG537_20515) - 4734618..4735007 (+) 390 WP_328830229.1 ATP-binding protein -
  OG537_RS20545 (OG537_20520) - 4735226..4735402 (-) 177 WP_328830230.1 CsbD family protein -
  OG537_RS20550 (OG537_20525) - 4735584..4735754 (+) 171 WP_266770719.1 hydrophobic protein -
  OG537_RS20555 (OG537_20530) - 4735958..4736311 (+) 354 WP_328830231.1 PRC-barrel domain containing protein -
  OG537_RS20560 (OG537_20535) - 4736569..4737408 (+) 840 WP_328830232.1 RNA polymerase sigma factor SigF -
  OG537_RS20565 (OG537_20540) vraR 4737471..4738163 (-) 693 WP_328933186.1 response regulator transcription factor Regulator
  OG537_RS20570 (OG537_20545) - 4738168..4739451 (-) 1284 WP_328936105.1 histidine kinase -
  OG537_RS20575 (OG537_20550) - 4739500..4740378 (-) 879 WP_328933187.1 CPBP family intramembrane glutamic endopeptidase -
  OG537_RS20585 (OG537_20560) - 4740819..4742378 (-) 1560 WP_328830236.1 amino acid permease -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 24733.51 Da        Isoelectric Point: 6.0270

>NTDB_id=653767 OG537_RS20565 WP_328933186.1 4737471..4738163(-) (vraR) [Streptomyces sp. NBC_00228]
MSEAPPPIRVLVCDDQELVRTGYVTIFSAQPDMEVVGEAENGHAAVEAARRLRPDVVVMDIRMPLLDGIEATRRLAAPGT
GEPPKVLVVTTFNVDAHVYDALRAGASGFLLKDAPPAELVNGIRTVARGEALLAPAVTRHLIGHYAEHLRPAESSRPARE
DVVSALTPRELEVLRQLAEGLSNAEIAAALYITPETVKTYVSRILAKLALRDRVQAVVLAYRVGLVSGTP

Nucleotide


Download         Length: 693 bp        

>NTDB_id=653767 OG537_RS20565 WP_328933186.1 4737471..4738163(-) (vraR) [Streptomyces sp. NBC_00228]
GTGAGCGAAGCGCCGCCACCGATCCGCGTGCTCGTCTGCGACGACCAGGAACTGGTGCGGACCGGCTACGTCACCATCTT
CTCGGCCCAGCCCGACATGGAGGTCGTCGGCGAGGCGGAGAACGGCCACGCGGCGGTGGAGGCCGCGCGACGGCTGCGCC
CCGACGTGGTCGTGATGGACATCCGGATGCCCCTCCTCGACGGCATCGAGGCGACCCGCCGACTGGCCGCCCCCGGCACC
GGGGAACCGCCGAAGGTGCTGGTCGTCACCACGTTCAACGTCGACGCCCATGTCTACGACGCGTTGCGCGCCGGAGCCAG
CGGGTTCCTCCTCAAGGACGCGCCGCCCGCGGAGCTGGTGAACGGCATCCGGACCGTCGCCCGGGGAGAGGCACTCCTGG
CGCCCGCCGTCACCCGCCACCTCATCGGCCACTACGCCGAGCACCTGCGCCCGGCCGAGTCGTCCCGGCCGGCCAGAGAG
GACGTCGTGAGCGCGCTGACGCCCCGTGAACTGGAGGTGCTCCGGCAGCTTGCCGAGGGGCTGTCGAACGCGGAGATAGC
GGCGGCGCTGTACATCACCCCCGAGACGGTCAAGACGTATGTCTCGCGGATTCTGGCCAAGCTAGCCCTGCGCGACCGGG
TCCAGGCGGTCGTCCTCGCCTACCGGGTCGGACTGGTGTCCGGCACCCCGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(10-123)

Bacterial regulatory proteins, luxR family (GerE)

(165-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.189

96.522

0.378
  degU Bacillus subtilis subsp. subtilis str. 168

36.564

98.696

0.361