Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG537_RS11760 Genome accession   NZ_CP108102
Coordinates   2749987..2750673 (-) Length   228 a.a.
NCBI ID   WP_328932297.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00228     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2744987..2755673
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG537_RS11735 (OG537_11710) - 2745181..2746059 (-) 879 WP_328932293.1 ABC transporter permease -
  OG537_RS11740 (OG537_11715) - 2746049..2746864 (-) 816 WP_019072927.1 ABC transporter ATP-binding protein -
  OG537_RS11745 (OG537_11720) - 2747024..2747716 (+) 693 WP_328932294.1 response regulator -
  OG537_RS11750 (OG537_11725) - 2747768..2749360 (-) 1593 WP_328932295.1 cation acetate symporter -
  OG537_RS11755 (OG537_11730) - 2749357..2749917 (-) 561 WP_328932296.1 DUF485 domain-containing protein -
  OG537_RS11760 (OG537_11735) vraR 2749987..2750673 (-) 687 WP_328932297.1 response regulator transcription factor Regulator
  OG537_RS11765 (OG537_11740) - 2750670..2751821 (-) 1152 WP_328932298.1 histidine kinase -
  OG537_RS11770 (OG537_11745) - 2751818..2752342 (-) 525 WP_328932299.1 DUF1453 domain-containing protein -
  OG537_RS11775 (OG537_11750) - 2752920..2755040 (-) 2121 WP_266773248.1 DNA topoisomerase IV subunit B -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 24118.63 Da        Isoelectric Point: 4.8483

>NTDB_id=653743 OG537_RS11760 WP_328932297.1 2749987..2750673(-) (vraR) [Streptomyces sp. NBC_00228]
MTEEPVKRPARVVVADDQTVVREGIVMLLGLLPGIEVVGAAGDGDEAVRLVAELAPDVVLMDLRMPRCDGVEATRQIRAG
YPGTQVVVLTTFADDASLFPALRAGARGYLTKDAGGDEIVRAVESVLSGDAGLSPSIQRRLLERLSEPEPQPVSGPAEPP
DGLTAREAEVLVLIAEGLTNQEIARALHVSTATVKTHINNLFAKTGLKDRAQAVRYAYGKGLVRPPAS

Nucleotide


Download         Length: 687 bp        

>NTDB_id=653743 OG537_RS11760 WP_328932297.1 2749987..2750673(-) (vraR) [Streptomyces sp. NBC_00228]
ATGACGGAGGAGCCCGTGAAGAGGCCCGCGCGGGTCGTGGTCGCGGACGACCAGACCGTCGTACGGGAAGGTATCGTGAT
GCTGCTGGGGCTGCTGCCCGGGATCGAGGTCGTCGGCGCCGCCGGTGACGGGGACGAGGCGGTGCGGCTCGTCGCCGAAC
TAGCCCCGGACGTCGTGCTGATGGACCTGCGCATGCCGCGCTGCGACGGCGTCGAGGCGACCCGGCAGATCCGTGCCGGC
TATCCCGGTACGCAGGTGGTGGTGCTCACGACGTTCGCGGACGACGCGTCGCTGTTCCCGGCGCTGCGTGCGGGGGCGCG
GGGCTATCTCACCAAGGACGCGGGCGGCGACGAGATCGTACGGGCCGTGGAGAGCGTGCTGTCGGGGGACGCGGGGCTGT
CGCCGAGCATCCAACGCCGGTTGCTGGAGCGGTTGTCGGAGCCCGAGCCGCAGCCGGTGTCCGGGCCCGCCGAGCCGCCG
GACGGGCTCACCGCGCGGGAGGCGGAGGTGCTGGTGCTGATCGCCGAGGGCCTGACCAACCAGGAGATCGCCCGCGCGTT
GCATGTCTCCACGGCGACGGTGAAGACCCACATCAACAACCTGTTCGCCAAGACGGGGCTCAAGGACCGTGCGCAGGCGG
TGCGTTACGCCTACGGGAAAGGACTGGTGCGGCCACCAGCGAGTTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(162-217)

Response regulator receiver domain (Response_reg)

(12-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.72

93.86

0.373
  degU Bacillus subtilis subsp. subtilis str. 168

37.387

97.368

0.364