Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG230_RS11040 Genome accession   NZ_CP108101
Coordinates   2533560..2534240 (+) Length   226 a.a.
NCBI ID   WP_328909995.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00234     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2528560..2539240
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG230_RS11020 (OG230_11020) - 2528983..2529648 (+) 666 WP_328909991.1 TetR family transcriptional regulator -
  OG230_RS11025 (OG230_11025) - 2529880..2531088 (+) 1209 WP_328909992.1 alpha/beta hydrolase -
  OG230_RS11030 (OG230_11030) - 2531174..2532124 (+) 951 WP_328909993.1 DUF4429 domain-containing protein -
  OG230_RS11035 (OG230_11035) - 2532232..2533563 (+) 1332 WP_328909994.1 sensor histidine kinase -
  OG230_RS11040 (OG230_11040) vraR 2533560..2534240 (+) 681 WP_328909995.1 response regulator transcription factor Regulator
  OG230_RS11045 (OG230_11045) - 2534406..2535449 (+) 1044 WP_328909996.1 alpha/beta hydrolase -
  OG230_RS11050 (OG230_11050) - 2535446..2536654 (+) 1209 WP_328909997.1 acyltransferase -
  OG230_RS11055 (OG230_11055) - 2536678..2537691 (-) 1014 WP_328909998.1 aldo/keto reductase -
  OG230_RS11060 (OG230_11060) - 2537691..2538152 (-) 462 WP_328909999.1 MerR family transcriptional regulator -
  OG230_RS11065 (OG230_11065) - 2538229..2539047 (+) 819 WP_328910000.1 serine hydrolase domain-containing protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24182.96 Da        Isoelectric Point: 5.7017

>NTDB_id=653672 OG230_RS11040 WP_328909995.1 2533560..2534240(+) (vraR) [Streptomyces sp. NBC_00234]
MTIRVIIVDDQAMVRAGFAALLAAQSDIDVVGEAPDGRRAIEVSRHQHPDVVLMDVRMPEMDGLAAARELLNPPVGVIHR
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLIAAVRVVAAGDALLAPSVTRRLIADFAAQRPSGAARSGAALRLN
GLTPRETEVLELIARGLSNQEIAERLVLAEQTVKTHIGRVLAKLDLRDRAQAVIFAYESGLVTPGS

Nucleotide


Download         Length: 681 bp        

>NTDB_id=653672 OG230_RS11040 WP_328909995.1 2533560..2534240(+) (vraR) [Streptomyces sp. NBC_00234]
GTGACCATCCGCGTGATCATCGTCGACGACCAGGCCATGGTGCGCGCGGGGTTCGCGGCACTGCTGGCGGCGCAGAGCGA
CATCGACGTGGTGGGTGAGGCCCCGGACGGACGCCGGGCCATCGAGGTCAGCCGCCATCAGCATCCGGACGTGGTGCTGA
TGGACGTGCGGATGCCCGAGATGGACGGGCTGGCGGCGGCCCGTGAGCTGTTGAACCCGCCCGTGGGCGTGATCCACCGG
CCGAAGGTGCTGATGCTCACCACCTTCGACGTGGACGACTACGTGTACGAGGCGCTGCGCGCGGGCGCGTCCGGCTTCCT
GCTGAAGGACGCGCCGCCCGCCGACCTGATCGCCGCGGTACGGGTGGTGGCGGCGGGGGACGCGCTGCTGGCCCCCTCCG
TGACCCGGCGGCTGATCGCGGACTTCGCGGCCCAGCGGCCGTCCGGAGCCGCCCGGAGCGGTGCCGCGCTGCGGCTGAAC
GGGCTGACCCCGCGGGAGACGGAGGTCCTGGAGCTGATCGCCCGGGGGCTGTCCAACCAGGAGATCGCTGAACGGCTGGT
GCTGGCCGAGCAGACGGTGAAGACCCACATCGGGCGGGTGCTGGCCAAGCTGGATCTGCGGGACCGGGCGCAGGCCGTGA
TCTTCGCGTACGAGTCGGGGCTGGTGACGCCGGGGAGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-121)

Bacterial regulatory proteins, luxR family (GerE)

(162-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.071

99.115

0.407
  degU Bacillus subtilis subsp. subtilis str. 168

38.326

100

0.385