Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG446_RS28995 Genome accession   NZ_CP108100
Coordinates   6480536..6481213 (+) Length   225 a.a.
NCBI ID   WP_328896766.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00236     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6475536..6486213
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG446_RS28975 (OG446_28995) - 6475911..6476144 (-) 234 WP_024489001.1 hypothetical protein -
  OG446_RS28980 (OG446_29000) - 6476579..6478699 (+) 2121 WP_219568111.1 DNA topoisomerase IV subunit B -
  OG446_RS28985 (OG446_29005) - 6478858..6479376 (+) 519 WP_328896764.1 DUF1453 domain-containing protein -
  OG446_RS28990 (OG446_29010) - 6479373..6480539 (+) 1167 WP_328896765.1 histidine kinase -
  OG446_RS28995 (OG446_29015) vraR 6480536..6481213 (+) 678 WP_328896766.1 response regulator transcription factor Regulator
  OG446_RS29000 (OG446_29020) - 6481312..6481788 (+) 477 WP_328896767.1 DUF485 domain-containing protein -
  OG446_RS29005 (OG446_29025) - 6481785..6483377 (+) 1593 WP_328896768.1 cation acetate symporter -
  OG446_RS29010 (OG446_29030) - 6483436..6483798 (-) 363 WP_328896769.1 DoxX family protein -
  OG446_RS29015 (OG446_29035) - 6483904..6484287 (+) 384 WP_328896770.1 helix-turn-helix domain-containing protein -
  OG446_RS29020 (OG446_29040) - 6484304..6484987 (-) 684 WP_328896771.1 response regulator -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 23976.42 Da        Isoelectric Point: 4.9580

>NTDB_id=653637 OG446_RS28995 WP_328896766.1 6480536..6481213(+) (vraR) [Streptomyces sp. NBC_00236]
MTARVVVADDQSVVREGIVMLLGLLPGIEVVGSAKDGEEAVALVAEHAPDVVLMDLRMPRCDGVEATRRIRKDFPGTQVV
VLTTFDDDDSLFPALRAGARGYLTKDAGGDEIVRAVHAVLSGEAGLSPAIQRRLLEQVTEGSLPRTGGDVLELPDGMTPR
EAEVLVLIADGMSNAEIARSLHISQATVKSHINNLFAKAGLRDRAQAVRYAYVRGIAQPPGTTFT

Nucleotide


Download         Length: 678 bp        

>NTDB_id=653637 OG446_RS28995 WP_328896766.1 6480536..6481213(+) (vraR) [Streptomyces sp. NBC_00236]
GTGACCGCGCGGGTGGTGGTCGCCGACGATCAGTCGGTGGTGCGTGAGGGGATCGTCATGCTGCTGGGGCTGCTGCCCGG
GATCGAGGTGGTCGGATCGGCGAAGGACGGGGAGGAAGCCGTCGCCCTTGTGGCCGAGCACGCCCCGGATGTTGTCCTGA
TGGACCTGCGGATGCCCCGCTGCGACGGGGTTGAGGCGACGCGCCGCATCCGCAAGGATTTCCCCGGCACACAGGTCGTG
GTGCTGACGACCTTCGACGACGACGACTCGCTCTTCCCGGCGCTCCGGGCGGGGGCCCGTGGATACCTGACGAAGGACGC
GGGGGGTGACGAGATCGTGCGGGCTGTCCACGCCGTGCTGTCCGGAGAGGCGGGGCTCTCGCCCGCCATTCAGCGCCGTC
TGCTGGAACAGGTCACCGAGGGGTCCCTGCCGCGGACGGGGGGCGATGTGCTGGAGCTGCCCGACGGGATGACTCCCCGC
GAGGCGGAGGTGCTCGTCCTGATCGCCGACGGGATGTCCAACGCGGAGATCGCCCGGAGCCTCCACATTTCGCAGGCCAC
CGTGAAGAGCCACATCAACAACCTGTTCGCCAAGGCCGGGCTCCGCGACCGGGCCCAGGCGGTCCGCTATGCGTACGTTC
GAGGGATCGCACAGCCGCCCGGGACAACCTTCACCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(157-211)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.45

96.889

0.382
  degU Bacillus subtilis subsp. subtilis str. 168

37.668

99.111

0.373