Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG446_RS20795 Genome accession   NZ_CP108100
Coordinates   4583224..4583862 (-) Length   212 a.a.
NCBI ID   WP_328895457.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00236     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4578224..4588862
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG446_RS20765 (OG446_20785) - 4578604..4579278 (-) 675 WP_328898356.1 rhomboid-like protein -
  OG446_RS20770 (OG446_20790) - 4579312..4580232 (+) 921 WP_328895453.1 aminoglycoside phosphotransferase family protein -
  OG446_RS20775 (OG446_20795) - 4580302..4580775 (+) 474 WP_328895454.1 GNAT family N-acetyltransferase -
  OG446_RS20780 (OG446_20800) - 4580789..4581790 (-) 1002 WP_328895455.1 zinc-binding dehydrogenase -
  OG446_RS20785 (OG446_20805) - 4581932..4582642 (+) 711 WP_328895456.1 pentapeptide repeat-containing protein -
  OG446_RS20790 (OG446_20810) - 4582664..4583161 (-) 498 WP_326659261.1 hypothetical protein -
  OG446_RS20795 (OG446_20815) vraR 4583224..4583862 (-) 639 WP_328895457.1 response regulator transcription factor Regulator
  OG446_RS20800 (OG446_20820) - 4583859..4585175 (-) 1317 WP_328898357.1 sensor histidine kinase -
  OG446_RS20805 (OG446_20825) - 4585341..4585898 (+) 558 WP_328895458.1 heme-binding protein -
  OG446_RS20810 (OG446_20830) - 4585932..4586546 (+) 615 WP_328895459.1 ankyrin repeat domain-containing protein -
  OG446_RS20815 (OG446_20835) - 4586543..4587661 (+) 1119 WP_328895460.1 hypothetical protein -

Sequence

Protein


Download         Length: 212 a.a.        Molecular weight: 22418.75 Da        Isoelectric Point: 5.3410

>NTDB_id=653613 OG446_RS20795 WP_328895457.1 4583224..4583862(-) (vraR) [Streptomyces sp. NBC_00236]
MTAPHPPVRILLCDDHAVVRAGLLALLGSEPDIEVVGEAGSGEEAVALTAKLTPDVVLMDLQLGEGIDGVETTRRIVAGT
AGAHVLVLTTYDTDADITRAIEAGATGYLLKAERPEELFAAIRSAAQGRTTLSPPVASRVMARMRAPLPTLTDRERDILG
QLSQGLGNRDIARALFISEATVKTHLGRIYDKLGVDTRAGAVSVAKEQRLLP

Nucleotide


Download         Length: 639 bp        

>NTDB_id=653613 OG446_RS20795 WP_328895457.1 4583224..4583862(-) (vraR) [Streptomyces sp. NBC_00236]
ATGACCGCTCCGCACCCGCCCGTCCGGATCCTGCTCTGCGACGACCACGCCGTCGTACGCGCCGGACTCCTCGCCCTCCT
CGGCAGCGAGCCCGACATCGAGGTCGTCGGCGAGGCCGGCAGCGGCGAGGAGGCCGTCGCCCTGACCGCCAAACTCACCC
CCGACGTCGTCCTGATGGACCTCCAGCTGGGCGAGGGCATCGACGGCGTCGAGACGACCCGACGCATCGTGGCCGGCACC
GCGGGCGCCCACGTCCTCGTCCTCACCACGTACGACACCGACGCCGACATCACCCGCGCCATCGAGGCGGGCGCCACCGG
CTACCTGCTGAAGGCCGAGCGCCCTGAGGAACTCTTCGCCGCGATCCGCTCCGCCGCCCAGGGCCGCACCACCCTGTCCC
CGCCCGTCGCCAGCCGCGTCATGGCCCGGATGCGCGCCCCCCTGCCCACCCTCACCGACCGCGAACGCGACATCCTGGGC
CAGCTCTCCCAAGGCCTCGGCAACCGCGACATCGCCCGCGCCCTGTTCATCAGCGAGGCCACCGTCAAAACCCACCTGGG
CCGCATCTACGACAAACTCGGCGTCGACACCCGGGCCGGCGCGGTCTCCGTCGCCAAGGAACAACGGCTTCTGCCCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(150-205)

Response regulator receiver domain (Response_reg)

(10-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.904

98.113

0.392
  degU Bacillus subtilis subsp. subtilis str. 168

35.78

100

0.368