Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG446_RS10350 Genome accession   NZ_CP108100
Coordinates   2326049..2326747 (+) Length   232 a.a.
NCBI ID   WP_328893746.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00236     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2321049..2331747
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG446_RS10330 (OG446_10345) - 2321389..2322069 (+) 681 WP_328898262.1 TetR family transcriptional regulator -
  OG446_RS10335 (OG446_10350) - 2322285..2323496 (+) 1212 WP_328893743.1 alpha/beta hydrolase -
  OG446_RS10340 (OG446_10355) - 2323613..2324560 (+) 948 WP_328893744.1 DUF4429 domain-containing protein -
  OG446_RS10345 (OG446_10360) - 2324661..2326052 (+) 1392 WP_328893745.1 sensor histidine kinase -
  OG446_RS10350 (OG446_10365) vraR 2326049..2326747 (+) 699 WP_328893746.1 response regulator transcription factor Regulator
  OG446_RS10355 (OG446_10370) - 2326997..2328040 (+) 1044 WP_328893747.1 alpha/beta hydrolase -
  OG446_RS10360 (OG446_10375) - 2328040..2329248 (+) 1209 WP_328893748.1 acyltransferase -
  OG446_RS10365 (OG446_10380) - 2329331..2330347 (-) 1017 WP_328893749.1 aldo/keto reductase -
  OG446_RS10370 (OG446_10385) - 2330374..2330814 (-) 441 WP_328893750.1 MerR family transcriptional regulator -
  OG446_RS10375 (OG446_10390) - 2331020..2331559 (+) 540 WP_328893751.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 232 a.a.        Molecular weight: 24515.28 Da        Isoelectric Point: 5.6365

>NTDB_id=653585 OG446_RS10350 WP_328893746.1 2326049..2326747(+) (vraR) [Streptomyces sp. NBC_00236]
MTIRVIIVDDQAMVRAGFAALLAAQSDIDVVGEAPDGRQGVDVSRHTHPDVVLMDVRMPEMDGLAAARELLNPPVGVVHV
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLISAVRVVAAGDALLAPSVTRRLIADFARQRPSGASRGGPALRLN
GLTPRETEVLELIARGLSNQEIAGHLVLAEQTVKTHIGRVLAKLDLRDRAQAVIFAYEAGLVVPGTPGPSGS

Nucleotide


Download         Length: 699 bp        

>NTDB_id=653585 OG446_RS10350 WP_328893746.1 2326049..2326747(+) (vraR) [Streptomyces sp. NBC_00236]
GTGACCATCCGTGTGATCATCGTCGACGACCAGGCCATGGTGCGGGCAGGATTCGCGGCGCTGCTGGCGGCGCAGTCCGA
CATCGACGTGGTCGGTGAGGCGCCGGACGGCCGCCAGGGTGTCGACGTCAGCCGCCACACCCATCCGGACGTGGTCCTGA
TGGATGTGCGGATGCCCGAGATGGACGGCCTGGCGGCGGCCCGTGAGCTGTTGAACCCGCCGGTGGGCGTGGTGCACGTG
CCGAAGGTGCTGATGCTCACCACTTTCGACGTGGACGACTACGTGTACGAGGCGCTGCGCGCCGGTGCGTCCGGGTTCCT
GTTGAAGGACGCCCCGCCGGCGGACCTGATCTCGGCGGTCCGGGTGGTGGCGGCCGGGGACGCGCTGCTGGCGCCGTCCG
TGACGCGGCGCCTGATCGCGGACTTCGCCCGGCAGCGGCCGTCCGGGGCCTCCCGCGGCGGGCCGGCGCTGCGGCTGAAC
GGGCTGACCCCGCGCGAGACGGAGGTGCTGGAGCTGATCGCGCGGGGGCTGTCGAACCAGGAGATCGCGGGGCATCTGGT
GCTTGCGGAGCAGACCGTGAAGACCCACATCGGCCGGGTGCTGGCCAAGCTGGACCTGCGCGACCGCGCCCAGGCGGTGA
TCTTCGCGTACGAGGCGGGGCTGGTGGTGCCGGGCACACCCGGCCCGTCCGGCAGTTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(162-216)

Response regulator receiver domain (Response_reg)

(5-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.179

96.552

0.388
  degU Bacillus subtilis subsp. subtilis str. 168

38.865

98.707

0.384