Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG446_RS02195 Genome accession   NZ_CP108100
Coordinates   494175..494840 (-) Length   221 a.a.
NCBI ID   WP_328892401.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00236     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 489175..499840
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG446_RS02170 (OG446_02170) - 489975..491189 (-) 1215 WP_328892396.1 ROK family protein -
  OG446_RS02175 (OG446_02175) - 491452..492576 (+) 1125 WP_328892397.1 MFS transporter -
  OG446_RS02180 (OG446_02180) - 492686..493057 (+) 372 WP_328892398.1 hypothetical protein -
  OG446_RS02185 (OG446_02185) - 493079..493831 (+) 753 WP_328892399.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OG446_RS02190 (OG446_02190) - 493900..494214 (+) 315 WP_328892400.1 DUF6332 family protein -
  OG446_RS02195 (OG446_02195) vraR 494175..494840 (-) 666 WP_328892401.1 response regulator transcription factor Regulator
  OG446_RS02200 (OG446_02200) - 494837..496177 (-) 1341 WP_328892402.1 sensor histidine kinase -
  OG446_RS02205 (OG446_02205) - 496311..497033 (-) 723 WP_328892403.1 TetR/AcrR family transcriptional regulator -
  OG446_RS02210 (OG446_02210) - 497161..497613 (+) 453 WP_328892404.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  OG446_RS02215 (OG446_02215) - 497763..498977 (-) 1215 WP_328892405.1 geranylgeranyl reductase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23967.66 Da        Isoelectric Point: 4.7038

>NTDB_id=653571 OG446_RS02195 WP_328892401.1 494175..494840(-) (vraR) [Streptomyces sp. NBC_00236]
MIRVLLADDQLLVRAGFRALLDAQPDIEVAGEAADGEEAVRLVRELRPDAVLMDIRMPHLDGLAATRAITGDPEFDAVKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPEELLRAVRAVVGGDALLSPGVTRRLIAEFAARSKEPTAATALNELTDRER
EVMALVGIGLSNDEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=653571 OG446_RS02195 WP_328892401.1 494175..494840(-) (vraR) [Streptomyces sp. NBC_00236]
GTGATTCGCGTACTGCTCGCCGATGACCAGCTGCTGGTCCGGGCGGGATTCCGGGCCCTGCTGGACGCCCAGCCGGACAT
CGAGGTCGCGGGCGAGGCGGCCGACGGCGAGGAGGCCGTCCGCCTGGTGCGTGAACTGCGGCCGGACGCCGTGCTGATGG
ACATCCGGATGCCACACCTCGACGGTCTCGCGGCGACCCGTGCCATCACCGGGGACCCGGAGTTCGACGCTGTGAAGGTG
GTCATGCTCACCACCTTCGAACTCGACGAGTACGTCTTCGAGGCGATCCGCTCCGGAGCCTCCGGTTTCCTGGTCAAGGA
CACCGAACCGGAAGAGCTGCTGCGGGCGGTCCGGGCGGTGGTCGGTGGGGACGCGCTCCTGTCGCCGGGTGTCACGCGCC
GGCTGATCGCCGAGTTCGCGGCCCGTTCCAAGGAGCCCACCGCGGCGACCGCCCTGAACGAACTGACCGACCGGGAGCGG
GAGGTGATGGCGTTGGTCGGCATCGGCCTGTCCAACGACGAGATCGCCCGCCGTCTCGTCGTCAGCCCGCTCACCGCCAA
GACTCATGTCAGCCGGACCATGGTGAAGCTCGGCGCCCGTGACCGGGCCCAACTCGTTGTACTCGCTTACGAGTCGGGGC
TGGTGCGGCCGGGCTGGCTCGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(155-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.5

97.738

0.367
  degU Bacillus subtilis subsp. subtilis str. 168

35.556

100

0.362