Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT59_RS41850 Genome accession   NZ_CP108094
Coordinates   9389002..9389667 (+) Length   221 a.a.
NCBI ID   WP_326724942.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00243     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 9384002..9394667
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT59_RS41825 (OHT59_41850) - 9384823..9386028 (+) 1206 WP_326724936.1 geranylgeranyl reductase family protein -
  OHT59_RS41830 (OHT59_41855) - 9386083..9386532 (-) 450 WP_326724937.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  OHT59_RS41835 (OHT59_41860) - 9386770..9387507 (+) 738 WP_326724938.1 TetR/AcrR family transcriptional regulator -
  OHT59_RS41840 (OHT59_41865) - 9387522..9387713 (+) 192 WP_326724939.1 hypothetical protein -
  OHT59_RS41845 (OHT59_41870) - 9387767..9389005 (+) 1239 WP_326724940.1 sensor histidine kinase -
  OHT59_RS41850 (OHT59_41875) vraR 9389002..9389667 (+) 666 WP_326724942.1 response regulator transcription factor Regulator
  OHT59_RS41855 (OHT59_41880) - 9389628..9389984 (-) 357 WP_326724943.1 DUF6332 family protein -
  OHT59_RS41860 (OHT59_41885) - 9390057..9391553 (-) 1497 WP_326724945.1 MFS transporter -
  OHT59_RS41865 (OHT59_41890) - 9391639..9392034 (+) 396 WP_326724946.1 MarR family transcriptional regulator -
  OHT59_RS41870 (OHT59_41895) - 9392171..9392932 (-) 762 WP_326724947.1 CbtA family protein -
  OHT59_RS41875 (OHT59_41900) - 9392948..9393169 (-) 222 WP_326724948.1 CbtB-domain containing protein -
  OHT59_RS41880 (OHT59_41905) - 9393418..9394002 (+) 585 WP_326724949.1 histidine phosphatase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24220.95 Da        Isoelectric Point: 4.7333

>NTDB_id=653483 OHT59_RS41850 WP_326724942.1 9389002..9389667(+) (vraR) [Streptomyces sp. NBC_00243]
MIRVLLADDQLLVRAGFKALLDAQSDIEVSGEAADGEEALRQVRELRPDVVLMDIRMPRLDGLAATRRITDDTDLKDVKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPEELLRAVRAVVEGDALLSPGVTRRLISEFAARSKEPAAVASLAELTERER
EVMALVGIGLSNDEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=653483 OHT59_RS41850 WP_326724942.1 9389002..9389667(+) (vraR) [Streptomyces sp. NBC_00243]
GTGATCCGCGTACTGCTCGCCGACGACCAGTTGCTGGTGAGGGCAGGCTTCAAGGCGCTGCTCGACGCGCAGTCGGACAT
CGAGGTGTCCGGGGAGGCCGCCGACGGCGAGGAGGCGCTGCGCCAGGTACGCGAACTGCGCCCCGACGTCGTCCTGATGG
ACATCCGCATGCCCCGGCTCGACGGCCTCGCCGCGACCCGCCGCATCACCGACGACACCGACCTCAAGGACGTCAAGGTG
GTCATGCTCACCACCTTCGAGCTGGACGAGTACGTCTTCGAGGCGATCCGCTCCGGTGCCTCCGGCTTCCTGGTCAAGGA
CACCGAGCCGGAGGAACTCCTGCGCGCGGTACGGGCGGTGGTCGAGGGCGACGCGCTGCTCTCGCCCGGCGTGACCCGTC
GGTTGATCTCGGAGTTCGCGGCCCGCTCCAAGGAGCCCGCGGCAGTCGCGTCACTCGCCGAACTCACCGAGCGGGAACGG
GAGGTGATGGCCCTGGTCGGCATCGGCCTGTCCAACGACGAGATCGCCCGGCGCCTCGTCGTCAGCCCGCTCACGGCGAA
GACGCATGTCAGCCGGACCATGGTGAAGCTGGGGGCCCGTGACCGGGCCCAACTGGTCGTGCTGGCCTATGAGTCGGGGT
TGGTGCGGCCGGGCTGGCTGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-209)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.352

97.738

0.385
  degU Bacillus subtilis subsp. subtilis str. 168

36.444

100

0.371