Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT59_RS39630 Genome accession   NZ_CP108094
Coordinates   8902841..8903503 (-) Length   220 a.a.
NCBI ID   WP_326724567.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00243     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8897841..8908503
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT59_RS39610 (OHT59_39635) - 8898551..8899381 (-) 831 WP_326724563.1 alpha/beta fold hydrolase -
  OHT59_RS39615 (OHT59_39640) - 8899564..8900448 (+) 885 WP_326724564.1 RNA polymerase sigma-70 factor -
  OHT59_RS39620 (OHT59_39645) - 8900714..8901475 (+) 762 WP_326724565.1 GntR family transcriptional regulator -
  OHT59_RS39625 (OHT59_39650) - 8901584..8902741 (-) 1158 WP_326724566.1 ROK family transcriptional regulator -
  OHT59_RS39630 (OHT59_39655) vraR 8902841..8903503 (-) 663 WP_326724567.1 response regulator transcription factor Regulator
  OHT59_RS39635 (OHT59_39660) - 8903518..8904672 (-) 1155 WP_326724568.1 histidine kinase -
  OHT59_RS39640 (OHT59_39665) - 8904781..8905716 (+) 936 WP_326724569.1 ATP-binding cassette domain-containing protein -
  OHT59_RS39645 (OHT59_39670) - 8905719..8906441 (+) 723 WP_326724570.1 ABC transporter permease -
  OHT59_RS39650 (OHT59_39675) mug 8906502..8907050 (-) 549 WP_326726281.1 G/U mismatch-specific DNA glycosylase -
  OHT59_RS39655 (OHT59_39680) purB 8907047..8908489 (-) 1443 WP_326724571.1 adenylosuccinate lyase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23422.05 Da        Isoelectric Point: 4.7428

>NTDB_id=653479 OHT59_RS39630 WP_326724567.1 8902841..8903503(-) (vraR) [Streptomyces sp. NBC_00243]
MPVTVLLVDDEPLVRAGLRAVLEAQPDIEVVGEAADGAAVIPLVRQLRPDVVAMDVRMPLMDGIEATRAVLRTVADPPKI
LVVTTFENDEYVYEALRAGADGFLLKRARPAEIVHAVRLVAEGESLLFPASVRQLAAEYGDSAGNPAARAAMDRAALTER
EAEVLRLMTRGMSNAEIAARMIVGTETVKSHVSAVLAKLGARDRTQAVIAAYESGFVAPG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=653479 OHT59_RS39630 WP_326724567.1 8902841..8903503(-) (vraR) [Streptomyces sp. NBC_00243]
ATGCCGGTCACCGTTCTCCTCGTCGACGACGAACCTCTCGTACGCGCTGGTCTGCGCGCCGTCCTGGAGGCCCAGCCCGA
CATCGAGGTCGTCGGGGAGGCCGCCGACGGTGCCGCGGTGATCCCGCTGGTACGGCAACTGCGGCCCGACGTCGTCGCCA
TGGACGTACGGATGCCCCTGATGGACGGCATCGAGGCCACGCGCGCGGTGCTGCGGACCGTGGCAGATCCGCCGAAGATC
CTGGTGGTGACGACGTTCGAGAACGACGAGTACGTCTACGAGGCGCTGCGGGCGGGCGCCGACGGGTTTCTGCTGAAGCG
GGCGCGGCCCGCCGAGATCGTGCACGCGGTGCGGCTCGTCGCCGAGGGCGAGTCGCTGCTGTTCCCCGCTTCCGTACGGC
AGTTGGCCGCCGAGTACGGGGACAGCGCGGGGAATCCCGCGGCGCGGGCGGCCATGGATCGGGCGGCCCTGACCGAGCGG
GAGGCGGAGGTGCTGCGGCTGATGACGCGGGGGATGTCGAACGCCGAGATCGCCGCTCGGATGATCGTCGGGACCGAGAC
GGTCAAGTCCCATGTCAGCGCCGTACTGGCGAAGCTGGGGGCCCGGGATCGTACGCAGGCGGTCATCGCGGCGTACGAGT
CGGGGTTCGTTGCGCCCGGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(156-210)

Response regulator receiver domain (Response_reg)

(5-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.096

99.545

0.409
  degU Bacillus subtilis subsp. subtilis str. 168

36.283

100

0.373