Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT59_RS21655 Genome accession   NZ_CP108094
Coordinates   4904275..4904991 (-) Length   238 a.a.
NCBI ID   WP_326721649.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00243     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4899275..4909991
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT59_RS21635 (OHT59_21640) - 4899477..4899893 (-) 417 WP_326721645.1 hypothetical protein -
  OHT59_RS21640 (OHT59_21645) - 4900028..4900729 (-) 702 WP_326721646.1 response regulator transcription factor -
  OHT59_RS21645 (OHT59_21650) - 4900726..4902738 (-) 2013 WP_326721647.1 sensor histidine kinase -
  OHT59_RS21650 (OHT59_21655) - 4902968..4904188 (-) 1221 WP_326721648.1 cytochrome P450 -
  OHT59_RS21655 (OHT59_21660) vraR 4904275..4904991 (-) 717 WP_326721649.1 response regulator transcription factor Regulator
  OHT59_RS21660 (OHT59_21665) - 4904988..4906334 (-) 1347 WP_326721650.1 histidine kinase -
  OHT59_RS21665 (OHT59_21670) - 4906509..4907201 (-) 693 WP_326721651.1 response regulator transcription factor -
  OHT59_RS21670 (OHT59_21675) - 4907198..4908586 (-) 1389 WP_326726097.1 sensor histidine kinase -
  OHT59_RS21675 (OHT59_21680) - 4908738..4909967 (-) 1230 WP_326721652.1 acyltransferase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 25343.06 Da        Isoelectric Point: 4.7446

>NTDB_id=653445 OHT59_RS21655 WP_326721649.1 4904275..4904991(-) (vraR) [Streptomyces sp. NBC_00243]
MTGTTSGTTGGITSSAGNAIRVLIADDQVMVREGFSVLLGAMPDIEVVGEAVNGREAVERVRELAPDVVLMDIRMPEMNG
IEATREIVAANGAAKVLVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVAAGEALLAPSVTRRLITEFSKLAD
EPRLSATAQAAYGDLTDRETEVLVLIAQGLSNAEIATRLFVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPR

Nucleotide


Download         Length: 717 bp        

>NTDB_id=653445 OHT59_RS21655 WP_326721649.1 4904275..4904991(-) (vraR) [Streptomyces sp. NBC_00243]
ATGACGGGCACCACCAGCGGTACCACCGGCGGAATCACCAGTAGCGCCGGCAACGCCATCCGTGTGCTGATAGCCGATGA
CCAGGTGATGGTCCGCGAGGGCTTCTCCGTGCTGCTCGGCGCGATGCCGGACATCGAGGTGGTCGGCGAGGCGGTCAACG
GTCGGGAGGCCGTCGAGCGGGTCCGCGAGCTGGCCCCGGACGTCGTGCTGATGGACATCCGGATGCCGGAGATGAACGGG
ATCGAGGCGACCCGGGAGATCGTCGCCGCGAACGGCGCCGCGAAGGTGCTGGTCCTGACGACGTTCGACCTCGACGAGTA
CGTGTACCAGGCGCTGCGGGCGGGAGCCTCCGGCTTCCTCCTCAAGGACGCCTCGGCGCGCCAGCTCGCCGACGGGGTGA
GGGTGGTGGCGGCCGGGGAGGCGCTGCTCGCCCCCTCGGTCACCAGGCGGTTGATCACCGAGTTCTCCAAGCTCGCGGAC
GAGCCACGGCTCTCGGCCACGGCACAGGCGGCGTACGGCGACCTCACCGACCGGGAGACCGAGGTGCTGGTCCTCATCGC
GCAGGGCCTGTCGAACGCGGAGATCGCGACCCGACTGTTCGTCGCCGAGTCCACGATCAAGACCCATGTGAGCCGGATCC
TGGTGAAGCTGGGCCTGCGGGACCGTACACAGGCGGCGGTGTTCGCGTACGAGGCACGGCTGGTCACGCCCAGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(22-131)

Bacterial regulatory proteins, luxR family (GerE)

(175-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.981

90.756

0.399
  degU Bacillus subtilis subsp. subtilis str. 168

41.593

94.958

0.395