Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT59_RS12675 Genome accession   NZ_CP108094
Coordinates   2893023..2893700 (-) Length   225 a.a.
NCBI ID   WP_326720249.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00243     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2888023..2898700
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT59_RS12655 (OHT59_12660) - 2888373..2890145 (+) 1773 WP_326720245.1 sensor histidine kinase -
  OHT59_RS12660 (OHT59_12665) - 2890142..2890822 (+) 681 WP_326720246.1 response regulator -
  OHT59_RS12665 (OHT59_12670) - 2890841..2892433 (-) 1593 WP_326720247.1 cation acetate symporter -
  OHT59_RS12670 (OHT59_12675) - 2892430..2892918 (-) 489 WP_326720248.1 DUF485 domain-containing protein -
  OHT59_RS12675 (OHT59_12680) vraR 2893023..2893700 (-) 678 WP_326720249.1 response regulator transcription factor Regulator
  OHT59_RS12680 (OHT59_12685) - 2893697..2894848 (-) 1152 WP_326720250.1 histidine kinase -
  OHT59_RS12685 (OHT59_12690) - 2894845..2895372 (-) 528 WP_326720251.1 DUF1453 domain-containing protein -
  OHT59_RS12690 (OHT59_12695) - 2895863..2897986 (-) 2124 WP_326720252.1 DNA topoisomerase IV subunit B -
  OHT59_RS12695 (OHT59_12700) - 2898430..2898660 (+) 231 WP_121406526.1 hypothetical protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 24034.48 Da        Isoelectric Point: 4.6152

>NTDB_id=653408 OHT59_RS12675 WP_326720249.1 2893023..2893700(-) (vraR) [Streptomyces sp. NBC_00243]
MTDEEGRKPARVVVADDQTVVREGIVMLLGLLPGIEVVGAAGDGDEAVALVAELAPDVVLMDLRMPRCDGVEATRRIRAE
YPGTQVVVLTTYEDDESLFPALRAGARGYLTKDAGGDEIVRAVQSVLSGEAGLSPSVQRRLLERLSEPEPFAPPEAPDGL
TARETEVLLLIAEGLTNQEIARALHVSMATVKTHINNLFAKTGIKDRAQAVRYAYGKGLVRPPAG

Nucleotide


Download         Length: 678 bp        

>NTDB_id=653408 OHT59_RS12675 WP_326720249.1 2893023..2893700(-) (vraR) [Streptomyces sp. NBC_00243]
ATGACGGACGAGGAGGGGAGGAAGCCGGCGCGGGTCGTGGTGGCGGACGACCAGACCGTGGTGCGCGAGGGCATCGTGAT
GCTGCTGGGGCTGTTGCCCGGGATCGAGGTCGTCGGTGCGGCCGGAGACGGTGACGAGGCTGTGGCGCTTGTCGCCGAAC
TCGCCCCGGACGTCGTGCTGATGGATCTGCGGATGCCTCGTTGCGACGGTGTCGAGGCGACCCGGCGCATCCGTGCCGAG
TACCCGGGAACGCAGGTCGTGGTGCTCACCACGTACGAGGACGACGAATCTCTGTTCCCCGCGCTCAGAGCGGGGGCGCG
GGGCTATCTGACCAAGGACGCGGGAGGTGACGAGATCGTCAGAGCGGTGCAGAGCGTGCTCTCCGGGGAGGCGGGGCTCT
CGCCGAGTGTCCAACGGCGGCTGCTGGAGCGGCTGTCGGAGCCGGAGCCGTTCGCGCCTCCGGAAGCGCCGGACGGGCTC
ACCGCCCGCGAGACGGAAGTGCTGCTCCTGATCGCCGAGGGCCTCACCAACCAGGAGATCGCCCGCGCGTTGCATGTGTC
CATGGCGACGGTGAAGACGCATATCAACAACCTCTTCGCCAAGACGGGGATCAAGGACCGTGCTCAGGCAGTCCGTTACG
CCTATGGGAAGGGTCTCGTACGGCCACCGGCCGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(159-214)

Response regulator receiver domain (Response_reg)

(12-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.758

93.778

0.382
  degU Bacillus subtilis subsp. subtilis str. 168

37.387

98.667

0.369