Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT52_RS28320 Genome accession   NZ_CP108093
Coordinates   6570071..6570721 (-) Length   216 a.a.
NCBI ID   WP_328723008.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00247     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6565071..6575721
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT52_RS28295 (OHT52_28280) - 6565092..6565856 (+) 765 WP_328723005.1 GntR family transcriptional regulator -
  OHT52_RS28300 (OHT52_28285) - 6565912..6567069 (-) 1158 WP_328723935.1 ROK family transcriptional regulator -
  OHT52_RS28305 (OHT52_28290) - 6567426..6568266 (+) 841 Protein_5569 IS5 family transposase -
  OHT52_RS28310 (OHT52_28295) - 6568333..6568776 (-) 444 WP_328723006.1 helix-turn-helix domain-containing protein -
  OHT52_RS28315 (OHT52_28300) - 6568909..6569781 (+) 873 WP_328723007.1 aldo/keto reductase family oxidoreductase -
  OHT52_RS28320 (OHT52_28305) vraR 6570071..6570721 (-) 651 WP_328723008.1 response regulator transcription factor Regulator
  OHT52_RS28325 (OHT52_28310) - 6570726..6571898 (-) 1173 WP_328723009.1 histidine kinase -
  OHT52_RS28330 (OHT52_28315) - 6572007..6572939 (+) 933 WP_328723010.1 ATP-binding cassette domain-containing protein -
  OHT52_RS28335 (OHT52_28320) - 6572936..6573685 (+) 750 WP_328723011.1 ABC transporter permease -
  OHT52_RS28340 (OHT52_28325) mug 6573947..6574504 (-) 558 WP_328723012.1 G/U mismatch-specific DNA glycosylase -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23199.11 Da        Isoelectric Point: 6.9930

>NTDB_id=653384 OHT52_RS28320 WP_328723008.1 6570071..6570721(-) (vraR) [Streptomyces sp. NBC_00247]
MTVNVLLVDDEPLVRTGLRAVLESQPDIVVAGEAADGAAVLPLVRQLRPDVVAMDVRMPLMDGIEATRLLLRTLAAPPKI
LVVTTFENDEYVYEALRAGADGFLLKRARPMEIVNAVRLVAEGESLLFPAAVRRLASEYGTNKARAVVTRAALTDREAAV
LRLMCRGLSNAEIAAKLVVGTETVKTHVSALLTKLGARDRTQAVITAYESGFVVPG

Nucleotide


Download         Length: 651 bp        

>NTDB_id=653384 OHT52_RS28320 WP_328723008.1 6570071..6570721(-) (vraR) [Streptomyces sp. NBC_00247]
GTGACGGTGAATGTTCTTCTCGTCGACGACGAGCCTCTCGTGCGGACGGGTCTGCGGGCGGTGCTGGAGTCGCAGCCGGA
CATCGTGGTGGCAGGGGAGGCCGCGGACGGCGCGGCGGTGCTCCCCCTGGTCCGACAACTGCGACCGGACGTGGTAGCCA
TGGACGTTCGGATGCCCTTGATGGACGGCATAGAGGCAACCCGGCTGCTGCTCCGCACATTGGCCGCACCGCCGAAGATC
CTGGTGGTCACGACGTTCGAGAACGACGAGTACGTGTACGAGGCGCTGCGTGCCGGTGCGGACGGTTTCCTGCTGAAGCG
AGCCCGGCCGATGGAGATCGTGAACGCGGTCCGGCTGGTGGCGGAAGGCGAGTCACTGCTCTTTCCCGCAGCCGTACGCC
GGCTGGCCTCCGAGTACGGGACGAACAAGGCCCGTGCGGTGGTGACGCGGGCGGCCCTCACCGACCGGGAGGCAGCCGTG
CTCCGGTTGATGTGTCGGGGTCTGTCGAACGCGGAGATTGCGGCGAAGCTGGTCGTGGGCACCGAGACGGTGAAAACCCA
TGTCAGTGCGTTGCTGACCAAGCTCGGGGCCCGAGACCGGACTCAGGCCGTCATCACCGCCTACGAGTCGGGCTTCGTGG
TCCCCGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-207)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.845

98.611

0.403
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.366