Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT52_RS22340 Genome accession   NZ_CP108093
Coordinates   5131960..5132640 (-) Length   226 a.a.
NCBI ID   WP_328721958.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00247     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5126960..5137640
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT52_RS22315 (OHT52_22295) - 5127037..5128251 (-) 1215 WP_328721953.1 acyltransferase -
  OHT52_RS22320 (OHT52_22300) - 5128248..5129324 (-) 1077 WP_328721954.1 alpha/beta hydrolase -
  OHT52_RS22325 (OHT52_22305) cpt 5129629..5130162 (-) 534 WP_328721955.1 chloramphenicol phosphotransferase CPT -
  OHT52_RS22330 (OHT52_22310) - 5130159..5131415 (-) 1257 WP_328721956.1 MFS transporter -
  OHT52_RS22335 (OHT52_22315) - 5131598..5131918 (-) 321 WP_328721957.1 hypothetical protein -
  OHT52_RS22340 (OHT52_22320) vraR 5131960..5132640 (-) 681 WP_328721958.1 response regulator transcription factor Regulator
  OHT52_RS22345 (OHT52_22325) - 5132637..5134109 (-) 1473 WP_328721959.1 sensor histidine kinase -
  OHT52_RS22350 (OHT52_22330) - 5134362..5135300 (-) 939 WP_328721960.1 DUF4429 domain-containing protein -
  OHT52_RS22355 (OHT52_22335) - 5135387..5136598 (-) 1212 WP_328721961.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24169.92 Da        Isoelectric Point: 5.8519

>NTDB_id=653371 OHT52_RS22340 WP_328721958.1 5131960..5132640(-) (vraR) [Streptomyces sp. NBC_00247]
MTIRVIIVDDQAMVRAGFAALLSAQSDIDVVGEAPDGRRGIEVSRDRRPDVVLMDVRMPEMDGLAAARALLDPPVGVVHR
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLITAVRVVAAGDALLAPSVTRRLIADFAAQRPSGASRSGQALRLN
GLTPRETEVLELIARGLSNQEIAGRLVLAEQTVKTHIGRVLAKLDLRDRAQAVIFAYESGLVTPGS

Nucleotide


Download         Length: 681 bp        

>NTDB_id=653371 OHT52_RS22340 WP_328721958.1 5131960..5132640(-) (vraR) [Streptomyces sp. NBC_00247]
GTGACCATCCGCGTGATCATCGTCGACGACCAGGCCATGGTGCGGGCCGGGTTCGCGGCCCTGCTGTCGGCGCAGAGCGA
CATCGACGTGGTGGGCGAGGCGCCGGACGGCCGCCGGGGCATAGAGGTGAGCCGCGACCGCCGTCCCGACGTGGTCCTGA
TGGACGTCCGGATGCCCGAGATGGACGGACTCGCCGCCGCCCGCGCCCTGTTGGACCCACCGGTCGGCGTGGTGCACCGC
CCGAAGGTGCTGATGCTCACGACGTTCGACGTGGACGACTACGTGTACGAGGCGCTGCGCGCCGGGGCCTCCGGGTTCCT
TCTGAAGGATGCGCCTCCTGCCGATCTGATCACGGCGGTACGAGTGGTGGCGGCGGGCGACGCGCTGCTCGCACCCTCCG
TGACGCGGCGGCTGATCGCGGACTTCGCCGCCCAGCGGCCGTCCGGCGCCTCCCGCAGCGGGCAGGCGCTCCGGCTGAAC
GGGCTGACCCCCCGGGAGACCGAGGTGCTGGAGCTGATCGCGCGCGGGCTCTCCAACCAGGAGATCGCGGGCCGGCTGGT
GCTGGCCGAGCAGACGGTGAAAACGCACATCGGGCGGGTGCTCGCCAAGCTGGACCTGCGGGACCGCGCGCAGGCCGTGA
TCTTCGCGTACGAGTCGGGGCTGGTGACACCGGGGAGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-121)

Bacterial regulatory proteins, luxR family (GerE)

(162-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.704

98.673

0.412
  degU Bacillus subtilis subsp. subtilis str. 168

37.004

100

0.372