Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG259_RS35580 Genome accession   NZ_CP108088
Coordinates   7836308..7836973 (+) Length   221 a.a.
NCBI ID   WP_328945977.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00250     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7831308..7841973
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG259_RS35555 (OG259_35580) - 7831882..7833261 (+) 1380 WP_328947274.1 geranylgeranyl reductase family protein -
  OG259_RS35560 (OG259_35585) - 7833349..7833801 (-) 453 WP_328947275.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  OG259_RS35565 (OG259_35590) - 7834069..7834764 (+) 696 WP_328945975.1 TetR/AcrR family transcriptional regulator -
  OG259_RS35570 (OG259_35595) - 7834844..7835010 (+) 167 Protein_7020 glyoxalase/bleomycin resistance/dioxygenase family protein -
  OG259_RS35575 (OG259_35600) - 7835094..7836311 (+) 1218 WP_328945976.1 sensor histidine kinase -
  OG259_RS35580 (OG259_35605) vraR 7836308..7836973 (+) 666 WP_328945977.1 response regulator transcription factor Regulator
  OG259_RS35585 (OG259_35610) - 7837133..7838686 (-) 1554 WP_328945978.1 MFS transporter -
  OG259_RS35590 (OG259_35615) - 7838774..7839172 (+) 399 WP_328945979.1 MarR family transcriptional regulator -
  OG259_RS35595 (OG259_35620) - 7839191..7839937 (-) 747 WP_328947276.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OG259_RS35600 (OG259_35625) - 7839997..7841226 (-) 1230 WP_328945980.1 MFS transporter -
  OG259_RS35605 (OG259_35630) - 7841519..7841752 (+) 234 WP_328945981.1 hypothetical protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23887.58 Da        Isoelectric Point: 4.8021

>NTDB_id=653326 OG259_RS35580 WP_328945977.1 7836308..7836973(+) (vraR) [Streptomyces sp. NBC_00250]
MIRVLLADDQSLVRAGFRALLDAQPDIEVAGEAADGGEAVERVRALRPDVVLMDIRMPGLDGLEATRRITDDPDLAEIRV
VMLTTFELDEYVFEAIRAGASGFLVKDTEPEELLRAVRAVVHGDALLSPGVTRRLIEEFAARSKAPGATAALGALTERER
EVMALVGIGLSNEEIARRLVVSPLTAKTHVSRAMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=653326 OG259_RS35580 WP_328945977.1 7836308..7836973(+) (vraR) [Streptomyces sp. NBC_00250]
GTGATCAGAGTGCTGCTCGCCGACGACCAGTCGCTGGTCCGGGCGGGGTTCCGCGCGCTGCTCGACGCCCAGCCGGACAT
CGAGGTGGCGGGCGAGGCCGCAGACGGCGGCGAGGCGGTGGAACGGGTGCGCGCCCTGCGCCCCGACGTCGTCCTCATGG
ACATCCGGATGCCCGGGCTCGACGGTCTTGAGGCCACCCGCCGCATCACGGACGACCCGGACCTCGCCGAGATCCGGGTC
GTCATGCTGACCACCTTCGAACTCGACGAGTACGTCTTCGAGGCGATCCGTGCCGGCGCCTCCGGCTTCCTGGTCAAGGA
CACCGAGCCGGAGGAACTGCTACGGGCGGTGCGTGCCGTCGTCCACGGCGACGCGCTGCTCTCCCCGGGCGTCACCCGCC
GGCTGATCGAGGAGTTCGCGGCCCGCTCCAAGGCCCCGGGAGCCACGGCGGCCCTCGGCGCGCTGACCGAGCGGGAGCGG
GAGGTGATGGCACTGGTCGGCATCGGCCTGTCGAACGAGGAGATCGCCCGCAGACTGGTCGTCAGCCCACTCACCGCCAA
GACCCACGTCAGCCGCGCCATGGTGAAGCTCGGCGCCCGGGACCGGGCCCAACTCGTCGTCCTGGCCTACGAGTCGGGAC
TCGTACGCCCAGGCTGGCTCGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-209)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.14

97.285

0.371
  degU Bacillus subtilis subsp. subtilis str. 168

36.283

100

0.371