Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG259_RS28450 Genome accession   NZ_CP108088
Coordinates   6302659..6303339 (-) Length   226 a.a.
NCBI ID   WP_328944840.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00250     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6297659..6308339
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG259_RS28425 (OG259_28435) - 6297799..6298629 (-) 831 WP_328944836.1 serine hydrolase domain-containing protein -
  OG259_RS28430 (OG259_28440) - 6298691..6299113 (+) 423 WP_328947198.1 MerR family transcriptional regulator -
  OG259_RS28435 (OG259_28445) - 6299110..6300135 (+) 1026 WP_328944837.1 aldo/keto reductase -
  OG259_RS28440 (OG259_28450) - 6300153..6301370 (-) 1218 WP_328944838.1 acyltransferase -
  OG259_RS28445 (OG259_28455) - 6301367..6302347 (-) 981 WP_328944839.1 alpha/beta hydrolase -
  OG259_RS28450 (OG259_28460) vraR 6302659..6303339 (-) 681 WP_328944840.1 response regulator transcription factor Regulator
  OG259_RS28455 (OG259_28465) - 6303336..6304628 (-) 1293 WP_328947199.1 sensor histidine kinase -
  OG259_RS28460 (OG259_28470) - 6304802..6305695 (-) 894 WP_328944841.1 DUF4429 domain-containing protein -
  OG259_RS28465 (OG259_28475) - 6305761..6306984 (-) 1224 WP_328944842.1 alpha/beta hydrolase -
  OG259_RS28470 (OG259_28480) - 6307137..6307796 (-) 660 WP_328944843.1 TetR family transcriptional regulator -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24133.82 Da        Isoelectric Point: 5.3264

>NTDB_id=653313 OG259_RS28450 WP_328944840.1 6302659..6303339(-) (vraR) [Streptomyces sp. NBC_00250]
MTIRVIIVDDQAMVRAGFAALLAAQPDIDVVGEAPDGRQGVDVARSTHPDVVLMDVRMPELDGLAAAREILHPPAGVTHR
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLIAAVRVVAAGEALLAPSVTRRLIADFAASRPAPRKDTTALRLNG
LTPRETEVLELIARGLSNQEIADHLVLAEQTVKTHIGRVLAKLDLRDRAQAVVFAYESGLVTPGTS

Nucleotide


Download         Length: 681 bp        

>NTDB_id=653313 OG259_RS28450 WP_328944840.1 6302659..6303339(-) (vraR) [Streptomyces sp. NBC_00250]
GTGACCATCCGCGTGATCATCGTCGACGACCAGGCCATGGTGCGGGCCGGTTTCGCCGCGCTGCTCGCCGCGCAACCCGA
CATCGACGTCGTGGGCGAGGCCCCGGACGGGCGGCAGGGCGTCGACGTGGCACGCTCGACGCACCCGGACGTGGTCCTCA
TGGACGTACGGATGCCGGAGCTGGACGGGCTCGCCGCCGCCCGGGAGATCCTCCACCCGCCGGCCGGGGTCACCCACCGG
CCGAAGGTGCTGATGCTGACCACCTTCGACGTGGACGACTACGTGTACGAGGCGCTGCGCGCCGGCGCGTCCGGCTTCCT
CCTGAAGGACGCGCCGCCGGCGGACCTGATCGCGGCGGTACGGGTGGTGGCGGCGGGCGAGGCGCTGCTCGCCCCGTCCG
TGACCCGGCGGCTGATCGCCGACTTCGCCGCCTCCCGGCCGGCGCCGCGCAAGGACACCACGGCGCTGCGCCTGAACGGT
CTCACCCCGCGCGAGACCGAGGTCCTGGAGCTCATCGCCCGCGGCCTGTCGAACCAGGAGATCGCGGACCATCTCGTCCT
CGCCGAGCAGACGGTGAAGACCCACATCGGCCGCGTCCTCGCCAAGCTGGACCTGCGCGACCGGGCGCAGGCGGTGGTCT
TCGCGTACGAGTCGGGCCTCGTGACCCCGGGCACGTCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-121)

Bacterial regulatory proteins, luxR family (GerE)

(161-215)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.819

97.788

0.389
  degU Bacillus subtilis subsp. subtilis str. 168

37.118

100

0.376