Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG259_RS22290 Genome accession   NZ_CP108088
Coordinates   4913512..4914171 (+) Length   219 a.a.
NCBI ID   WP_328943869.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00250     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4908512..4919171
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG259_RS22265 (OG259_22280) - 4908634..4909833 (-) 1200 WP_328943865.1 PP2C family protein-serine/threonine phosphatase -
  OG259_RS22270 (OG259_22285) - 4910260..4910929 (-) 670 Protein_4408 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
  OG259_RS22275 (OG259_22290) - 4910926..4911273 (-) 348 WP_328943866.1 transcriptional regulator -
  OG259_RS22280 (OG259_22295) - 4911780..4912415 (+) 636 WP_328943867.1 DUF998 domain-containing protein -
  OG259_RS22285 (OG259_22300) - 4912451..4913515 (+) 1065 WP_328943868.1 histidine kinase -
  OG259_RS22290 (OG259_22305) vraR 4913512..4914171 (+) 660 WP_328943869.1 response regulator transcription factor Regulator
  OG259_RS22295 (OG259_22310) - 4914401..4914625 (+) 225 WP_328947337.1 hypothetical protein -
  OG259_RS22300 (OG259_22315) - 4914622..4914732 (+) 111 Protein_4414 PRC-barrel domain containing protein -
  OG259_RS22305 (OG259_22320) - 4914967..4915305 (-) 339 WP_209495626.1 MerR family transcriptional regulator -
  OG259_RS22310 (OG259_22325) - 4915975..4916331 (+) 357 Protein_4416 hypothetical protein -
  OG259_RS22315 (OG259_22330) - 4916444..4916755 (-) 312 WP_328943870.1 SCO5918 family protein -
  OG259_RS22320 (OG259_22335) - 4916804..4917205 (-) 402 WP_328943871.1 hypothetical protein -
  OG259_RS22325 (OG259_22340) - 4917251..4918765 (-) 1515 WP_328943872.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23667.40 Da        Isoelectric Point: 6.6551

>NTDB_id=653289 OG259_RS22290 WP_328943869.1 4913512..4914171(+) (vraR) [Streptomyces sp. NBC_00250]
MTISVLLADDQALVRAGFRSLLGRAKILAVIGEAASGEEAVRQAALLRPDVVLMDIRMPGMDGIEATRLILAEQPTTRVI
ILTTFDTDEHVFEALQAGASGFLTKEVEPAELRRAVEVVAAGDSLLSPGVTRRVIERFAHRPRPTVTLHALTARENEVVR
LVAEGLSNDEIAAVLVISPLTVKTHISRAITKLGLRDRVQLVITAYEHGLVSASRTDGR

Nucleotide


Download         Length: 660 bp        

>NTDB_id=653289 OG259_RS22290 WP_328943869.1 4913512..4914171(+) (vraR) [Streptomyces sp. NBC_00250]
ATGACCATCAGTGTGCTGCTCGCCGACGACCAGGCGCTCGTGCGGGCGGGGTTCCGCAGCCTGCTCGGGCGCGCCAAGAT
CCTGGCCGTCATCGGCGAGGCCGCCTCGGGAGAGGAGGCGGTACGGCAGGCCGCCCTGCTGCGACCGGACGTCGTGCTGA
TGGACATCAGAATGCCGGGCATGGACGGCATCGAGGCCACCCGTCTCATCCTGGCCGAGCAGCCGACGACCAGGGTGATC
ATCCTGACCACGTTCGACACCGACGAGCACGTCTTCGAAGCGCTGCAGGCAGGGGCGAGCGGGTTCCTCACCAAGGAGGT
CGAACCGGCCGAACTACGTCGGGCGGTCGAGGTCGTGGCGGCGGGCGACTCCCTGCTGTCACCGGGCGTGACCCGCCGCG
TCATCGAGCGCTTCGCGCACCGCCCCCGGCCCACCGTCACACTGCACGCGCTGACGGCACGTGAGAACGAGGTGGTCAGG
TTGGTGGCGGAAGGGCTGTCCAATGACGAGATCGCCGCCGTACTGGTGATCAGCCCGCTGACCGTGAAGACCCACATCTC
CCGGGCCATCACCAAGTTGGGCCTGCGCGACCGTGTGCAACTGGTCATCACCGCCTACGAGCACGGTCTCGTCAGCGCCT
CGCGCACCGATGGTCGATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(150-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.284

96.347

0.388
  degU Bacillus subtilis subsp. subtilis str. 168

37.668

100

0.384