Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG259_RS19190 Genome accession   NZ_CP108088
Coordinates   4269863..4270483 (+) Length   206 a.a.
NCBI ID   WP_030223700.1    Uniprot ID   A0ABV3D1Y0
Organism   Streptomyces sp. NBC_00250     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4264863..4275483
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG259_RS19175 (OG259_19190) - 4266266..4267702 (-) 1437 WP_328943389.1 M1 family metallopeptidase -
  OG259_RS19180 (OG259_19195) - 4267807..4268346 (-) 540 WP_266894742.1 heme-binding protein -
  OG259_RS19185 (OG259_19200) - 4268655..4269863 (+) 1209 WP_328947123.1 sensor histidine kinase -
  OG259_RS19190 (OG259_19205) vraR 4269863..4270483 (+) 621 WP_030223700.1 response regulator transcription factor Regulator
  OG259_RS19195 (OG259_19210) - 4270587..4271792 (+) 1206 WP_328943390.1 FAD-dependent monooxygenase -
  OG259_RS19200 (OG259_19215) - 4271800..4272606 (-) 807 WP_328943391.1 ABC transporter permease -
  OG259_RS19205 (OG259_19220) - 4272603..4273601 (-) 999 WP_328943392.1 ATP-binding cassette domain-containing protein -
  OG259_RS19210 (OG259_19225) - 4273734..4275050 (+) 1317 WP_328943393.1 sensor histidine kinase -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 21623.01 Da        Isoelectric Point: 6.4939

>NTDB_id=653281 OG259_RS19190 WP_030223700.1 4269863..4270483(+) (vraR) [Streptomyces sp. NBC_00250]
MSVRILLCDDHVVVRAGLLALLGSTPDIEVVGEAGSGEEAVAMAAKLKPDVVLMDLQLGAGIDGVEATRLIAPTGVHVLV
LTTYDTDADITRAIEAGATGYLLKAERPEELFAAIHSAAQGRTALSPPVASRVMDRMRGAAGPSLTDRERDILGQLGRGL
GNREIARALFISEATVKTHLGRIYAKLGVDTRAGAVAVAKERRLLP

Nucleotide


Download         Length: 621 bp        

>NTDB_id=653281 OG259_RS19190 WP_030223700.1 4269863..4270483(+) (vraR) [Streptomyces sp. NBC_00250]
ATGTCCGTACGGATCCTCCTCTGCGACGACCACGTCGTCGTCCGCGCCGGCCTGCTGGCCCTGCTCGGCAGCACCCCCGA
CATCGAGGTCGTCGGCGAGGCCGGCAGCGGCGAGGAGGCCGTCGCGATGGCGGCGAAGCTGAAGCCGGACGTCGTCCTGA
TGGACCTGCAGCTCGGCGCGGGCATCGACGGCGTGGAGGCGACCCGGCTGATCGCCCCCACGGGAGTCCACGTCCTCGTT
CTCACCACGTACGACACGGACGCCGACATCACCCGGGCGATCGAGGCGGGCGCCACCGGCTACCTCCTGAAGGCCGAGCG
GCCCGAGGAACTGTTCGCCGCGATCCACTCGGCCGCCCAGGGCCGCACCGCCCTCTCCCCGCCGGTCGCCAGCCGGGTCA
TGGACCGGATGCGGGGCGCGGCGGGCCCGAGCCTCACGGACCGGGAGCGGGACATCCTGGGCCAGCTCGGCCGGGGCCTC
GGCAACCGCGAGATCGCGCGGGCCCTGTTCATCAGCGAGGCGACGGTGAAGACCCACCTGGGCCGCATCTACGCGAAGCT
CGGCGTCGACACGCGCGCGGGCGCCGTCGCGGTCGCGAAGGAACGACGCCTGCTGCCGTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(144-199)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40

100

0.408
  degU Bacillus subtilis subsp. subtilis str. 168

35

100

0.374