Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT77_RS37850 Genome accession   NZ_CP108087
Coordinates   8539714..8540376 (-) Length   220 a.a.
NCBI ID   WP_328832859.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00252     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8534714..8545376
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT77_RS37830 (OHT77_37840) - 8535334..8536164 (-) 831 WP_328832856.1 alpha/beta fold hydrolase -
  OHT77_RS37835 (OHT77_37845) - 8536332..8537216 (+) 885 WP_328832857.1 RNA polymerase sigma-70 factor -
  OHT77_RS37840 (OHT77_37850) - 8537457..8538218 (+) 762 WP_328832858.1 GntR family transcriptional regulator -
  OHT77_RS37845 (OHT77_37855) - 8538460..8539614 (-) 1155 WP_266766712.1 ROK family transcriptional regulator -
  OHT77_RS37850 (OHT77_37860) vraR 8539714..8540376 (-) 663 WP_328832859.1 response regulator transcription factor Regulator
  OHT77_RS37855 (OHT77_37865) - 8540391..8541545 (-) 1155 WP_328832860.1 histidine kinase -
  OHT77_RS37860 (OHT77_37870) - 8541654..8542574 (+) 921 WP_328832861.1 ABC transporter ATP-binding protein -
  OHT77_RS37865 (OHT77_37875) - 8542577..8543299 (+) 723 WP_328832862.1 ABC transporter permease -
  OHT77_RS37870 (OHT77_37880) mug 8543450..8543995 (-) 546 WP_328834447.1 G/U mismatch-specific DNA glycosylase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23524.14 Da        Isoelectric Point: 4.8723

>NTDB_id=653229 OHT77_RS37850 WP_328832859.1 8539714..8540376(-) (vraR) [Streptomyces sp. NBC_00252]
MPVTVLLVDDEPLVRAGLRAVLEAQPDIEVVGEAADGAAVIPLVRQLRPDVVAMDVRMPLLDGIEATRAVLRTVDDPPKI
LVITTFENDEYVYEALRAGADGFLLKRARPAEIVHAVRLVAEGESLLFPASVRQLAAEYGDGGGNRAARAVMERARLTER
EAEVLRLMARGLSNAEIAARLVVGTETVKSHVSAVLAKLGARDRTQAVIAAYESGFVAPG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=653229 OHT77_RS37850 WP_328832859.1 8539714..8540376(-) (vraR) [Streptomyces sp. NBC_00252]
ATGCCGGTCACCGTTCTCCTGGTCGATGACGAACCCCTCGTACGCGCGGGTCTGCGGGCCGTGCTGGAGGCGCAGCCGGA
CATCGAGGTGGTCGGGGAGGCCGCCGACGGGGCCGCGGTGATCCCGCTGGTGCGGCAGCTGCGGCCCGACGTGGTCGCCA
TGGACGTACGGATGCCACTCCTTGACGGCATCGAGGCCACGCGCGCGGTGCTGCGCACGGTCGACGATCCGCCGAAGATC
CTGGTCATCACGACCTTCGAGAACGACGAGTACGTCTACGAGGCTTTGCGCGCCGGTGCCGACGGGTTCCTGCTGAAGCG
GGCCCGGCCGGCCGAGATCGTGCACGCGGTACGCCTGGTGGCCGAGGGCGAGTCGCTGCTCTTCCCCGCCTCCGTACGGC
AGTTGGCCGCCGAGTACGGCGACGGCGGCGGGAACCGGGCGGCCCGCGCGGTGATGGAGCGGGCCCGGCTGACCGAGCGT
GAGGCCGAGGTGCTGCGGCTGATGGCGCGGGGTCTGTCGAACGCGGAGATCGCCGCGCGGCTGGTCGTCGGGACCGAGAC
GGTGAAGTCGCATGTGAGCGCCGTACTGGCGAAGCTGGGGGCCCGGGACCGTACGCAGGCGGTGATCGCGGCGTACGAGT
CGGGGTTCGTGGCGCCGGGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-118)

Bacterial regulatory proteins, luxR family (GerE)

(157-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.096

99.545

0.409
  degU Bacillus subtilis subsp. subtilis str. 168

36.607

100

0.373