Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT77_RS36395 Genome accession   NZ_CP108087
Coordinates   8192608..8193231 (-) Length   207 a.a.
NCBI ID   WP_328832614.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00252     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8187608..8198231
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT77_RS36375 (OHT77_36385) - 8188030..8189259 (-) 1230 WP_328832610.1 DUF349 domain-containing protein -
  OHT77_RS36380 (OHT77_36390) - 8189395..8190222 (-) 828 WP_328832611.1 peptidylprolyl isomerase -
  OHT77_RS36385 (OHT77_36395) - 8190402..8191121 (+) 720 WP_328832612.1 MBL fold metallo-hydrolase -
  OHT77_RS36390 (OHT77_36400) hisS 8191132..8192394 (+) 1263 WP_328832613.1 histidine--tRNA ligase -
  OHT77_RS36395 (OHT77_36405) vraR 8192608..8193231 (-) 624 WP_328832614.1 response regulator transcription factor Regulator
  OHT77_RS36400 (OHT77_36410) - 8193228..8194499 (-) 1272 WP_328832615.1 sensor histidine kinase -
  OHT77_RS36405 (OHT77_36415) - 8194496..8195347 (-) 852 WP_328832616.1 ABC transporter permease -
  OHT77_RS36410 (OHT77_36420) - 8195344..8196210 (-) 867 WP_328832617.1 ABC transporter ATP-binding protein -
  OHT77_RS36415 (OHT77_36425) - 8196353..8197009 (+) 657 WP_328832618.1 vitamin K epoxide reductase family protein -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 22146.64 Da        Isoelectric Point: 5.8568

>NTDB_id=653226 OHT77_RS36395 WP_328832614.1 8192608..8193231(-) (vraR) [Streptomyces sp. NBC_00252]
MIRIILADDHPVVREGLRAMLSAEPDLDVVADASSGPQAEALAAELRPDIVLMDLRMPGGGGVDSIVRMSAAGLPCRVIV
LTTYETDRDILRAVEAGAAGYLLKDLPRGELADAVRAAARGETVLAPSVAARLVDQLRTRPDRPRLSVREVAVLRLVAEG
CTNAEIGRRLYIGESTVKTHLLRVFGKLGVDDRTAAVTSAMRYGLLD

Nucleotide


Download         Length: 624 bp        

>NTDB_id=653226 OHT77_RS36395 WP_328832614.1 8192608..8193231(-) (vraR) [Streptomyces sp. NBC_00252]
ATGATCCGGATCATCCTGGCCGACGACCATCCCGTCGTACGGGAGGGCCTGCGCGCCATGCTCAGTGCCGAGCCGGATCT
CGATGTCGTCGCCGACGCGTCCAGTGGGCCTCAGGCGGAGGCGCTCGCGGCCGAACTCCGGCCCGACATCGTGCTGATGG
ACCTGCGGATGCCGGGGGGTGGGGGTGTCGACTCCATCGTGCGGATGAGTGCGGCGGGGTTGCCCTGCCGCGTCATCGTG
CTCACGACGTACGAGACCGACCGGGACATCCTGCGGGCCGTGGAGGCGGGGGCGGCGGGTTATCTGCTGAAGGATCTGCC
TCGGGGTGAACTCGCCGACGCGGTACGGGCCGCTGCGCGGGGCGAGACCGTGCTGGCGCCGTCCGTCGCGGCGCGGCTGG
TCGACCAGTTGCGGACCAGGCCCGATCGGCCTCGGTTGTCCGTGCGGGAGGTCGCGGTGTTGCGGTTGGTGGCGGAGGGG
TGCACCAACGCCGAGATCGGGCGGCGGCTGTACATCGGGGAGTCCACCGTGAAGACCCATCTGCTGCGGGTCTTCGGGAA
GTTGGGGGTGGATGACCGGACGGCGGCGGTGACGAGTGCGATGCGGTACGGGTTGCTGGACTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(146-200)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.379

99.517

0.372
  degU Bacillus subtilis subsp. subtilis str. 168

33.482

100

0.362