Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT77_RS24405 Genome accession   NZ_CP108087
Coordinates   5546640..5547308 (+) Length   222 a.a.
NCBI ID   WP_328830615.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00252     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5541640..5552308
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT77_RS24385 (OHT77_24390) kynU 5542163..5543353 (+) 1191 WP_328830612.1 kynureninase -
  OHT77_RS24390 (OHT77_24395) - 5543350..5544012 (-) 663 WP_328830613.1 TetR/AcrR family transcriptional regulator -
  OHT77_RS24395 (OHT77_24400) - 5544243..5545175 (+) 933 WP_328830614.1 alpha/beta hydrolase -
  OHT77_RS24400 (OHT77_24405) - 5545318..5546643 (+) 1326 WP_328834327.1 histidine kinase -
  OHT77_RS24405 (OHT77_24410) vraR 5546640..5547308 (+) 669 WP_328830615.1 response regulator transcription factor Regulator
  OHT77_RS24410 (OHT77_24415) - 5547424..5548647 (+) 1224 WP_328830616.1 cytochrome P450 -
  OHT77_RS24415 (OHT77_24420) - 5548680..5549234 (-) 555 WP_328830617.1 MarR family transcriptional regulator -
  OHT77_RS24420 (OHT77_24425) - 5549316..5550776 (+) 1461 WP_328830618.1 MFS transporter -
  OHT77_RS24425 (OHT77_24430) - 5550854..5551345 (-) 492 WP_328830619.1 hypothetical protein -
  OHT77_RS24430 (OHT77_24435) - 5551398..5552081 (-) 684 WP_328830620.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 23860.55 Da        Isoelectric Point: 4.5842

>NTDB_id=653198 OHT77_RS24405 WP_328830615.1 5546640..5547308(+) (vraR) [Streptomyces sp. NBC_00252]
MTIRVLIADDQMMVREGFSVLLGAMPDIEVVGEAVNGRDAVERVRELAPDVVLMDIRMPELNGIEATREIVAADGAAKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVAAGEALLAPSVTSRLITEFSKLADSPRVMPAAAQGTYGELT
ERETEVLVLIAQGLSNGEIAERLVVAESTIKTHVSRVLVKLGLRDRTQAAVFAYEARLVRPG

Nucleotide


Download         Length: 669 bp        

>NTDB_id=653198 OHT77_RS24405 WP_328830615.1 5546640..5547308(+) (vraR) [Streptomyces sp. NBC_00252]
ATGACCATCCGCGTGCTGATCGCGGACGACCAGATGATGGTGCGCGAGGGCTTCTCGGTCCTGTTGGGCGCGATGCCGGA
CATCGAGGTGGTCGGCGAGGCGGTGAACGGACGCGACGCGGTGGAGCGCGTACGCGAACTGGCCCCGGACGTGGTCCTGA
TGGACATCCGCATGCCGGAGCTGAACGGCATCGAGGCGACCCGGGAGATCGTCGCGGCGGACGGCGCGGCGAAGGTGCTG
GTGCTCACCACGTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGGGCGGGCGCCTCCGGCTTCCTCCTCAAGGACGC
CTCCGCACGTCAACTGGCCGACGGGGTGAGGGTGGTGGCGGCAGGCGAGGCCCTGCTCGCCCCCTCGGTCACCAGCCGGC
TGATCACGGAGTTCTCGAAGCTGGCCGACTCGCCCCGCGTGATGCCGGCCGCGGCGCAGGGGACGTACGGGGAGCTGACC
GAGCGGGAGACGGAGGTGCTGGTCCTCATCGCGCAGGGGTTGTCGAACGGGGAGATCGCCGAGCGGCTGGTGGTCGCCGA
GTCGACGATCAAGACCCACGTCAGCCGCGTCCTGGTGAAGCTGGGCCTCCGGGACCGGACCCAGGCGGCGGTGTTCGCGT
ACGAGGCGAGGCTGGTGAGGCCGGGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-114)

Bacterial regulatory proteins, luxR family (GerE)

(159-213)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.182

99.099

0.428
  degU Bacillus subtilis subsp. subtilis str. 168

42.661

98.198

0.419