Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT77_RS21930 Genome accession   NZ_CP108087
Coordinates   5028156..5028848 (-) Length   230 a.a.
NCBI ID   WP_328830233.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00252     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5023156..5033848
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT77_RS21900 (OHT77_21895) - 5024289..5024624 (-) 336 WP_328830228.1 MerR family transcriptional regulator -
  OHT77_RS21905 (OHT77_21900) - 5025305..5025694 (+) 390 WP_328830229.1 ATP-binding protein -
  OHT77_RS21910 (OHT77_21905) - 5025913..5026089 (-) 177 WP_328830230.1 CsbD family protein -
  OHT77_RS21915 (OHT77_21910) - 5026271..5026441 (+) 171 WP_266770719.1 hydrophobic protein -
  OHT77_RS21920 (OHT77_21915) - 5026645..5026998 (+) 354 WP_328830231.1 PRC-barrel domain containing protein -
  OHT77_RS21925 (OHT77_21920) - 5027254..5028093 (+) 840 WP_328830232.1 RNA polymerase sigma factor SigF -
  OHT77_RS21930 (OHT77_21925) vraR 5028156..5028848 (-) 693 WP_328830233.1 response regulator transcription factor Regulator
  OHT77_RS21935 (OHT77_21930) - 5028853..5030136 (-) 1284 WP_328830234.1 histidine kinase -
  OHT77_RS21940 (OHT77_21935) - 5030185..5031063 (-) 879 WP_328830235.1 CPBP family intramembrane glutamic endopeptidase -
  OHT77_RS21950 (OHT77_21945) - 5031504..5033063 (-) 1560 WP_328830236.1 amino acid permease -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 24691.43 Da        Isoelectric Point: 6.0270

>NTDB_id=653194 OHT77_RS21930 WP_328830233.1 5028156..5028848(-) (vraR) [Streptomyces sp. NBC_00252]
MSEAPPPIRVLVCDDQELVRTGYATIFSAQPDMEVVGEAENGHAAVEAARRLRPDVVVMDIRMPLLDGIEATRRLAAPGT
GEPPKVLVVTTFNVDAHVYDALRAGASGFLLKDAPPAELVNGIRTVARGEALLAPAVTRHLIGHYAEHLRPAESSRPGRE
DVVSALTPRELEVLRQLAEGLSNAEIAAALYITPETVKTYVSRILAKLALRDRVQAVVLAYRVGLVSGTP

Nucleotide


Download         Length: 693 bp        

>NTDB_id=653194 OHT77_RS21930 WP_328830233.1 5028156..5028848(-) (vraR) [Streptomyces sp. NBC_00252]
GTGAGCGAAGCGCCGCCACCGATCCGCGTGCTCGTCTGCGACGACCAGGAACTGGTGCGGACCGGCTACGCCACCATCTT
CTCGGCCCAGCCCGACATGGAGGTCGTCGGCGAGGCGGAGAACGGCCACGCGGCGGTGGAGGCCGCGCGACGGCTCCGCC
CCGACGTGGTCGTGATGGACATCCGGATGCCCCTCCTCGACGGCATCGAGGCGACCCGCCGACTGGCCGCCCCCGGCACC
GGGGAACCGCCGAAGGTGCTGGTCGTCACCACGTTCAACGTCGACGCCCATGTCTACGACGCGTTGCGCGCCGGAGCCAG
CGGGTTCCTCCTCAAGGACGCGCCGCCCGCGGAGCTGGTGAACGGCATCCGGACCGTCGCCCGGGGAGAGGCACTCCTGG
CACCCGCCGTCACCCGCCACCTCATCGGCCACTACGCCGAGCACCTGCGCCCGGCCGAGTCGTCCCGGCCGGGCAGAGAG
GACGTCGTGAGCGCGCTGACGCCCCGTGAACTGGAGGTGCTCCGGCAGCTGGCCGAGGGGCTGTCGAACGCGGAGATAGC
GGCGGCGCTGTACATCACCCCCGAGACGGTCAAGACGTATGTCTCGCGGATCCTGGCCAAGCTCGCCCTGCGCGACCGGG
TCCAGGCGGTCGTCCTCGCCTACCGGGTCGGACTGGTGTCCGGCACCCCGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(10-123)

Bacterial regulatory proteins, luxR family (GerE)

(165-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.189

96.522

0.378
  degU Bacillus subtilis subsp. subtilis str. 168

36.564

98.696

0.361