Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT77_RS11985 Genome accession   NZ_CP108087
Coordinates   2815436..2816122 (-) Length   228 a.a.
NCBI ID   WP_328828273.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00252     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2810436..2821122
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT77_RS11960 (OHT77_11945) - 2810630..2811508 (-) 879 WP_328828267.1 ABC transporter permease -
  OHT77_RS11965 (OHT77_11950) - 2811498..2812313 (-) 816 WP_328828269.1 ABC transporter ATP-binding protein -
  OHT77_RS11970 (OHT77_11955) - 2812473..2813165 (+) 693 WP_328828270.1 response regulator -
  OHT77_RS11975 (OHT77_11960) - 2813217..2814809 (-) 1593 WP_266773255.1 cation acetate symporter -
  OHT77_RS11980 (OHT77_11965) - 2814806..2815366 (-) 561 WP_328828272.1 DUF485 domain-containing protein -
  OHT77_RS11985 (OHT77_11970) vraR 2815436..2816122 (-) 687 WP_328828273.1 response regulator transcription factor Regulator
  OHT77_RS11990 (OHT77_11975) - 2816119..2817270 (-) 1152 WP_328828275.1 histidine kinase -
  OHT77_RS11995 (OHT77_11980) - 2817267..2817791 (-) 525 WP_328828276.1 DUF1453 domain-containing protein -
  OHT77_RS12000 (OHT77_11985) - 2818340..2820460 (-) 2121 WP_266773248.1 DNA topoisomerase IV subunit B -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 24122.64 Da        Isoelectric Point: 4.8483

>NTDB_id=653169 OHT77_RS11985 WP_328828273.1 2815436..2816122(-) (vraR) [Streptomyces sp. NBC_00252]
MTEEPMKRPARVVVADDQTVVREGIVMLLGLLPGIEVVGAAGDGDEAVRLVAELAPDVVLMDLRMPRCDGVEATRQIRAG
YPGTQVVVLTTFADDASLFPALRAGARGYLTKDAGGDEIVRAVESVLSGDAGLSPSIQRRLLERLSEPEPQPASGPAEPP
DGLTAREAEVLVLIAEGLTNQEIARALHVSTATVKTHINNLFAKTGLKDRAQAVRYAYGKGLVRPPAS

Nucleotide


Download         Length: 687 bp        

>NTDB_id=653169 OHT77_RS11985 WP_328828273.1 2815436..2816122(-) (vraR) [Streptomyces sp. NBC_00252]
ATGACGGAGGAGCCCATGAAGAGGCCGGCGAGGGTCGTGGTCGCGGACGACCAGACCGTCGTACGGGAAGGCATCGTGAT
GCTGCTGGGGCTGCTGCCCGGGATCGAGGTCGTCGGCGCCGCCGGTGACGGGGACGAGGCGGTGCGGCTCGTCGCCGAAC
TCGCCCCGGACGTCGTGCTGATGGACCTGCGCATGCCGCGCTGCGACGGCGTCGAGGCGACCCGGCAGATCCGTGCCGGC
TATCCCGGTACGCAGGTGGTGGTGCTCACGACGTTCGCGGACGACGCGTCGCTGTTCCCGGCGCTGCGCGCGGGGGCGCG
CGGCTATCTCACCAAGGACGCGGGCGGCGACGAGATCGTACGGGCCGTGGAGAGCGTGCTGTCGGGGGACGCGGGGCTGT
CGCCGAGCATCCAACGCCGGTTGCTGGAGCGGTTGTCGGAGCCCGAGCCGCAGCCGGCGTCCGGGCCCGCCGAGCCGCCG
GACGGGCTCACCGCGCGGGAGGCGGAGGTGCTGGTGCTGATCGCCGAGGGCCTGACCAACCAGGAGATCGCCCGCGCGTT
GCATGTCTCCACGGCAACGGTGAAGACCCACATCAACAACCTGTTCGCCAAGACGGGGCTCAAGGACCGTGCGCAGGCGG
TGCGTTACGCCTACGGGAAAGGACTGGTGCGGCCACCAGCGAGTTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(162-217)

Response regulator receiver domain (Response_reg)

(12-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.72

93.86

0.373
  degU Bacillus subtilis subsp. subtilis str. 168

38.288

97.368

0.373