Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT77_RS00520 Genome accession   NZ_CP108087
Coordinates   131812..132447 (-) Length   211 a.a.
NCBI ID   WP_328825869.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00252     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 126812..137447
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT77_RS00490 (OHT77_00490) - 126894..127364 (-) 471 WP_328825861.1 hypothetical protein -
  OHT77_RS00495 (OHT77_00495) - 127855..128529 (-) 675 WP_328825863.1 SDR family NAD(P)-dependent oxidoreductase -
  OHT77_RS00500 (OHT77_00500) - 128659..129372 (+) 714 WP_328825864.1 TetR/AcrR family transcriptional regulator -
  OHT77_RS00505 (OHT77_00505) - 130195..130401 (+) 207 WP_328825865.1 hypothetical protein -
  OHT77_RS00510 (OHT77_00510) - 130398..130781 (+) 384 WP_328825866.1 hypothetical protein -
  OHT77_RS00515 (OHT77_00515) - 131142..131408 (-) 267 WP_328825867.1 hypothetical protein -
  OHT77_RS00520 (OHT77_00520) vraR 131812..132447 (-) 636 WP_328825869.1 response regulator transcription factor Regulator
  OHT77_RS00525 (OHT77_00525) - 132444..133664 (-) 1221 WP_328825870.1 sensor histidine kinase -
  OHT77_RS00530 (OHT77_00530) - 133837..134925 (+) 1089 WP_328825871.1 FtsX-like permease family protein -
  OHT77_RS00535 (OHT77_00535) - 134922..135605 (+) 684 WP_328825873.1 ABC transporter ATP-binding protein -
  OHT77_RS00540 (OHT77_00540) - 136166..137371 (+) 1206 WP_328825874.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 22054.15 Da        Isoelectric Point: 5.0698

>NTDB_id=653154 OHT77_RS00520 WP_328825869.1 131812..132447(-) (vraR) [Streptomyces sp. NBC_00252]
MTDTPIRLLLADDHPVVRAGLRAVLETEPGLVVTAEAATAEAAVTRAAEGDIDVVLMDLQFGGRMGGAEATAQITARPGA
PRVLIVTTYDSDADTLPAIEAGATGYLLKDAPPEDLAAAVRTAAAGRITLAPTVADRLMNRLRTPGTTLTRRESEVLTLV
ADGLSNQAIGNRLHLTEGTVKSHLARIYTKLDVDSRTAAVAAATDLGLIRR

Nucleotide


Download         Length: 636 bp        

>NTDB_id=653154 OHT77_RS00520 WP_328825869.1 131812..132447(-) (vraR) [Streptomyces sp. NBC_00252]
GTGACCGACACCCCCATCCGCCTGCTCCTGGCCGACGACCACCCCGTCGTACGGGCCGGACTGCGCGCCGTGCTGGAAAC
CGAGCCCGGCCTCGTCGTCACGGCCGAAGCCGCCACCGCCGAGGCCGCCGTCACCCGCGCCGCCGAGGGCGACATCGACG
TCGTGCTCATGGACCTCCAGTTCGGCGGGCGCATGGGCGGCGCCGAAGCCACCGCCCAGATCACCGCCCGCCCCGGAGCC
CCCCGTGTACTGATCGTCACCACCTACGACTCCGACGCCGACACCCTGCCCGCCATCGAAGCCGGCGCCACCGGCTACCT
CCTCAAAGACGCCCCGCCCGAGGACCTGGCCGCCGCCGTACGTACCGCAGCCGCCGGACGCATCACACTGGCGCCCACAG
TCGCCGACCGGCTGATGAACCGGCTCCGCACACCAGGCACCACTCTGACCCGGCGCGAGAGCGAAGTCCTCACCCTGGTC
GCCGACGGCCTGTCCAACCAAGCCATCGGCAACCGGCTCCACCTGACCGAAGGCACCGTCAAATCCCACCTCGCCCGCAT
CTACACCAAACTCGACGTCGACTCACGCACCGCCGCCGTCGCTGCCGCCACCGATCTCGGCCTCATCCGGCGTTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(9-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.5

98.578

0.37
  degU Bacillus subtilis subsp. subtilis str. 168

33.628

100

0.36