Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHU11_RS38245 Genome accession   NZ_CP108082
Coordinates   8567732..8568397 (+) Length   221 a.a.
NCBI ID   WP_266692533.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00257     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8562732..8573397
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHU11_RS38225 (OHU11_38205) - 8563801..8565015 (+) 1215 WP_266692526.1 geranylgeranyl reductase family protein -
  OHU11_RS38230 (OHU11_38210) - 8565090..8565542 (-) 453 WP_266692528.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  OHU11_RS38235 (OHU11_38215) - 8565671..8566378 (+) 708 WP_266692530.1 TetR/AcrR family transcriptional regulator -
  OHU11_RS38240 (OHU11_38220) - 8566473..8567735 (+) 1263 WP_266772040.1 sensor histidine kinase -
  OHU11_RS38245 (OHU11_38225) vraR 8567732..8568397 (+) 666 WP_266692533.1 response regulator transcription factor Regulator
  OHU11_RS38250 (OHU11_38230) - 8568497..8570002 (-) 1506 WP_266692535.1 MFS transporter -
  OHU11_RS38255 (OHU11_38235) - 8570090..8570491 (+) 402 WP_266692537.1 MarR family transcriptional regulator -
  OHU11_RS38260 (OHU11_38240) - 8570543..8571298 (-) 756 WP_266772043.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OHU11_RS38265 (OHU11_38245) - 8571342..8572565 (-) 1224 WP_266692539.1 MFS transporter -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24026.73 Da        Isoelectric Point: 4.7221

>NTDB_id=653149 OHU11_RS38245 WP_266692533.1 8567732..8568397(+) (vraR) [Streptomyces sp. NBC_00257]
MIRVLLADDQSLVRAGFRALLDAQPDIEVAGEAADGAEAVRLVGELRPDIVLMDIRMPRLDGLAATRAITEDARLDDVRV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPDELLRAVRAVVGGDALLSPGVTRRLIAEFAARSKEPAEATGLRELTERER
EVMALVGIGLSNEEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=653149 OHU11_RS38245 WP_266692533.1 8567732..8568397(+) (vraR) [Streptomyces sp. NBC_00257]
GTGATCCGCGTACTGCTCGCCGACGACCAGTCGCTGGTCCGGGCGGGCTTCCGGGCCCTGCTGGACGCCCAGCCCGACAT
CGAGGTGGCCGGGGAGGCCGCCGACGGCGCGGAGGCCGTGCGCCTGGTGGGTGAACTGCGGCCCGACATCGTGCTGATGG
ACATCCGGATGCCGCGTCTCGACGGTCTCGCCGCGACCCGCGCCATCACCGAGGACGCCCGGCTGGACGACGTCAGGGTG
GTCATGCTCACCACCTTCGAGCTCGACGAGTACGTCTTCGAGGCGATCCGCTCCGGGGCCTCCGGCTTCCTGGTCAAGGA
CACCGAACCCGATGAACTGCTGCGCGCCGTACGGGCGGTGGTGGGCGGCGACGCCCTGCTGTCGCCGGGGGTCACCCGGC
GCCTGATCGCCGAGTTCGCGGCCCGCTCCAAGGAGCCCGCGGAGGCGACCGGGCTGCGCGAGCTGACCGAACGGGAGCGG
GAGGTGATGGCGCTCGTCGGCATAGGTCTCTCCAACGAGGAGATCGCCCGGCGCCTCGTCGTCAGCCCGCTCACCGCCAA
GACCCATGTGAGCCGAACCATGGTGAAGCTGGGAGCCCGCGACCGGGCCCAACTCGTCGTGCTCGCCTACGAGTCGGGGC
TGGTGCGGCCGGGCTGGCTCGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-209)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.605

97.285

0.376
  degU Bacillus subtilis subsp. subtilis str. 168

36

100

0.367