Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHU11_RS36995 Genome accession   NZ_CP108082
Coordinates   8283766..8284416 (-) Length   216 a.a.
NCBI ID   WP_259934545.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00257     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8278766..8289416
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHU11_RS36975 (OHU11_36960) - 8279489..8280319 (-) 831 WP_266692240.1 alpha/beta fold hydrolase -
  OHU11_RS36980 (OHU11_36965) sigJ 8280474..8281388 (+) 915 WP_266692241.1 RNA polymerase sigma factor SigJ -
  OHU11_RS36985 (OHU11_36970) - 8281640..8282407 (+) 768 WP_266771844.1 GntR family transcriptional regulator -
  OHU11_RS36990 (OHU11_36975) - 8282509..8283666 (-) 1158 WP_266692243.1 ROK family protein -
  OHU11_RS36995 (OHU11_36980) vraR 8283766..8284416 (-) 651 WP_259934545.1 response regulator transcription factor Regulator
  OHU11_RS37000 (OHU11_36985) - 8284575..8285768 (-) 1194 WP_259934544.1 histidine kinase -
  OHU11_RS37005 (OHU11_36990) - 8285877..8286815 (+) 939 WP_266692245.1 ATP-binding cassette domain-containing protein -
  OHU11_RS37010 (OHU11_36995) - 8286818..8287555 (+) 738 WP_266692247.1 ABC transporter permease -
  OHU11_RS37015 (OHU11_37000) - 8287670..8288107 (+) 438 WP_266771848.1 hypothetical protein -
  OHU11_RS37020 (OHU11_37005) mug 8288291..8288881 (-) 591 WP_266692249.1 G/U mismatch-specific DNA glycosylase -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23014.72 Da        Isoelectric Point: 5.1311

>NTDB_id=653146 OHU11_RS36995 WP_259934545.1 8283766..8284416(-) (vraR) [Streptomyces sp. NBC_00257]
MPVSVLLVDDEPLVRAGLRAVLEAQPDIEVVGEAGDGAAVIPLLHQLRPDVVAMDVRMPLMDGIEATRVVLRTVPNPPKI
LVVTTFENDEYVYEALRAGADGFLIKRARPSEIVNAVRLVAEGESLLFPAAVRQLAAEYGTSKARAAMDRAALTERESTV
LRLMARGLSNAEIAAKLVVGVETVKTHVSAVLAKLGARDRTQAVIAAYESGFVAPG

Nucleotide


Download         Length: 651 bp        

>NTDB_id=653146 OHU11_RS36995 WP_259934545.1 8283766..8284416(-) (vraR) [Streptomyces sp. NBC_00257]
ATGCCGGTTAGCGTACTTCTGGTCGACGACGAACCCCTCGTCCGCGCGGGGCTGCGCGCGGTCCTTGAGGCTCAGCCCGA
TATCGAGGTGGTGGGCGAGGCGGGCGACGGCGCCGCCGTGATCCCGCTGCTGCACCAGCTGCGGCCGGACGTGGTGGCCA
TGGATGTCAGGATGCCGTTGATGGACGGTATCGAGGCCACGCGGGTGGTGCTGCGTACGGTGCCGAATCCGCCGAAGATC
CTCGTGGTGACCACATTCGAGAACGACGAGTACGTCTACGAGGCGCTGCGTGCCGGTGCGGACGGCTTCCTCATCAAACG
TGCCCGGCCCTCCGAGATCGTGAATGCGGTGCGTCTGGTGGCCGAGGGTGAGTCGCTGCTCTTCCCGGCGGCGGTCCGGC
AGCTCGCCGCCGAGTACGGGACGAGCAAGGCGCGTGCGGCCATGGACCGGGCAGCGCTCACCGAGCGGGAATCCACGGTC
CTGAGGCTGATGGCCCGTGGCCTGTCCAACGCCGAGATCGCCGCCAAACTCGTGGTCGGCGTCGAGACGGTGAAGACCCA
TGTCAGCGCGGTGCTGGCCAAGTTGGGTGCCAGGGACCGCACTCAGGCGGTGATCGCGGCGTACGAATCCGGGTTCGTCG
CCCCGGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-118)

Bacterial regulatory proteins, luxR family (GerE)

(152-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.254

98.611

0.417
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.37