Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHU11_RS29705 Genome accession   NZ_CP108082
Coordinates   6641121..6641804 (-) Length   227 a.a.
NCBI ID   WP_266691029.1    Uniprot ID   A0ABW2X1G6
Organism   Streptomyces sp. NBC_00257     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6636121..6646804
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHU11_RS29670 (OHU11_29645) - 6636621..6636887 (-) 267 WP_266771071.1 DUF397 domain-containing protein -
  OHU11_RS29675 (OHU11_29650) - 6636847..6637695 (-) 849 Protein_5864 helix-turn-helix transcriptional regulator -
  OHU11_RS29680 (OHU11_29655) - 6637845..6638267 (+) 423 WP_266772752.1 ATP-binding protein -
  OHU11_RS29685 (OHU11_29660) - 6638227..6639048 (-) 822 WP_266771073.1 serine hydrolase domain-containing protein -
  OHU11_RS29690 (OHU11_29665) - 6639166..6639627 (+) 462 WP_266691026.1 MerR family transcriptional regulator -
  OHU11_RS29695 (OHU11_29670) - 6639627..6640643 (+) 1017 WP_266771076.1 aldo/keto reductase -
  OHU11_RS29700 (OHU11_29675) - 6640784..6641071 (+) 288 WP_266691028.1 hypothetical protein -
  OHU11_RS29705 (OHU11_29680) vraR 6641121..6641804 (-) 684 WP_266691029.1 response regulator transcription factor Regulator
  OHU11_RS29710 (OHU11_29685) - 6641801..6643144 (-) 1344 WP_266691030.1 sensor histidine kinase -
  OHU11_RS29715 (OHU11_29690) - 6643261..6644229 (-) 969 WP_266691031.1 DUF4429 domain-containing protein -
  OHU11_RS29720 (OHU11_29695) - 6644315..6645526 (-) 1212 WP_266691032.1 alpha/beta hydrolase -
  OHU11_RS29725 (OHU11_29700) - 6645801..6646472 (-) 672 WP_266691033.1 TetR family transcriptional regulator -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 24140.87 Da        Isoelectric Point: 5.1172

>NTDB_id=653135 OHU11_RS29705 WP_266691029.1 6641121..6641804(-) (vraR) [Streptomyces sp. NBC_00257]
MTIRVIIVDDQAMVRAGFAALLSAQSDIDVVGEAPDGRQGVEVGRSTRPDVVLMDVRMPEMDGLAAARELLNPPVGVVHR
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLISAVRVVAAGEALLAPSVTRRLIADFARQGPTGATRSGQSLRLN
GLTPRETEVLELIARGLSNQEIAGKLVLAEQTVKTHIGRVLAKLDLRDRAQAVIFAYEAGVVVPGEG

Nucleotide


Download         Length: 684 bp        

>NTDB_id=653135 OHU11_RS29705 WP_266691029.1 6641121..6641804(-) (vraR) [Streptomyces sp. NBC_00257]
TTGACCATCCGTGTGATCATCGTCGACGACCAGGCCATGGTGCGGGCGGGGTTCGCGGCGCTGCTGTCGGCGCAGAGCGA
CATCGATGTGGTCGGTGAGGCACCGGACGGGCGCCAGGGCGTCGAGGTCGGCCGCAGCACCCGTCCGGACGTGGTGCTGA
TGGACGTCCGGATGCCGGAGATGGACGGCCTGGCGGCGGCCCGTGAGCTGCTGAACCCGCCGGTGGGGGTGGTGCACCGG
CCGAAGGTCCTGATGCTCACCACGTTCGACGTGGACGACTACGTGTACGAGGCGCTGCGCGCCGGGGCGTCCGGCTTCCT
GCTGAAGGACGCGCCGCCGGCCGACCTGATCTCGGCGGTGCGGGTGGTCGCGGCGGGCGAGGCACTGCTCGCGCCGTCCG
TGACGCGCCGTCTGATCGCGGACTTCGCCCGGCAGGGCCCGACCGGGGCCACCCGGAGCGGCCAGTCACTGCGGCTGAAC
GGGCTGACTCCGCGCGAGACGGAGGTGCTGGAGCTGATCGCGCGGGGCCTGTCCAACCAGGAGATCGCGGGGAAGCTGGT
ACTGGCCGAGCAGACCGTGAAGACGCATATCGGCCGGGTCCTGGCCAAGCTGGACCTGCGGGACCGGGCACAGGCGGTGA
TCTTCGCGTACGAGGCGGGGGTGGTGGTGCCGGGCGAGGGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-121)

Bacterial regulatory proteins, luxR family (GerE)

(162-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.286

98.678

0.388
  degU Bacillus subtilis subsp. subtilis str. 168

37.004

100

0.37