Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHU11_RS23875 Genome accession   NZ_CP108082
Coordinates   5317095..5317772 (+) Length   225 a.a.
NCBI ID   WP_124719602.1    Uniprot ID   A0ABW2X2K0
Organism   Streptomyces sp. NBC_00257     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5312095..5322772
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHU11_RS23855 (OHU11_23835) - 5312665..5313513 (+) 849 WP_124719606.1 tryptophan 2,3-dioxygenase family protein -
  OHU11_RS23860 (OHU11_23840) kynU 5313506..5314720 (+) 1215 WP_266690049.1 kynureninase -
  OHU11_RS23865 (OHU11_23845) - 5314816..5315691 (+) 876 WP_266690050.1 alpha/beta hydrolase -
  OHU11_RS23870 (OHU11_23850) - 5315797..5317098 (+) 1302 WP_266690051.1 histidine kinase -
  OHU11_RS23875 (OHU11_23855) vraR 5317095..5317772 (+) 678 WP_124719602.1 response regulator transcription factor Regulator
  OHU11_RS23880 (OHU11_23860) - 5317898..5319127 (+) 1230 WP_266690052.1 cytochrome P450 -
  OHU11_RS23885 (OHU11_23865) - 5319210..5319539 (-) 330 WP_266690053.1 hypothetical protein -
  OHU11_RS23890 (OHU11_23870) - 5319675..5320367 (+) 693 WP_266690054.1 alpha/beta hydrolase -
  OHU11_RS23895 (OHU11_23875) - 5320532..5322166 (-) 1635 WP_266770383.1 ABC transporter permease -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 24139.96 Da        Isoelectric Point: 4.9545

>NTDB_id=653119 OHU11_RS23875 WP_124719602.1 5317095..5317772(+) (vraR) [Streptomyces sp. NBC_00257]
MSTPTVPSIRVLIVDDQMMVREGFSVLLNAMPGIEVVGEAVDGRQAIAQVAALRPDVVLMDIRMPELNGIEATREIVAAD
ADAKVLVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVAAGEALLAPTVTKRLINEFSKLAEAPRSPALARVG
DLTERETEVLVLIAQGRSNAEIASHLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPS

Nucleotide


Download         Length: 678 bp        

>NTDB_id=653119 OHU11_RS23875 WP_124719602.1 5317095..5317772(+) (vraR) [Streptomyces sp. NBC_00257]
ATGAGCACTCCCACCGTCCCGTCCATCCGGGTGCTGATCGTGGACGACCAGATGATGGTCCGCGAGGGCTTCTCGGTGCT
GCTCAACGCCATGCCGGGGATCGAGGTCGTCGGCGAGGCCGTCGACGGCCGGCAGGCCATCGCACAGGTCGCGGCGCTGC
GCCCCGATGTGGTCCTGATGGACATCCGGATGCCGGAACTCAACGGCATCGAGGCCACCCGCGAGATCGTCGCCGCCGAC
GCGGACGCCAAGGTCCTGGTGCTGACCACCTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGCGCCGGGGCGTCCGG
CTTCCTCCTCAAGGACGCCTCCGCGCGCCAGCTCGCGGACGGGGTACGGGTGGTGGCCGCGGGCGAGGCGCTGCTCGCGC
CGACCGTGACCAAGCGGCTGATCAACGAGTTCTCGAAGCTCGCGGAGGCCCCGCGCTCGCCCGCGCTGGCCCGGGTCGGC
GATCTCACCGAGCGCGAGACGGAGGTGCTCGTCCTCATCGCGCAGGGCCGGTCCAACGCCGAGATCGCCTCGCATCTGGT
GGTCGCCGAGTCCACCATCAAGACGCATGTGAGCCGGATCCTGGTGAAGCTGGGGCTGCGCGACCGCACCCAGGCGGCCG
TCTTCGCGTACGAGGCCCGGCTGGTCACACCGTCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(11-120)

Bacterial regulatory proteins, luxR family (GerE)

(162-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.116

95.556

0.431
  degU Bacillus subtilis subsp. subtilis str. 168

43.119

96.889

0.418