Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHU11_RS20270 Genome accession   NZ_CP108082
Coordinates   4549145..4549774 (+) Length   209 a.a.
NCBI ID   WP_266689464.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00257     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4544145..4554774
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHU11_RS20250 (OHU11_20230) - 4545177..4546187 (-) 1011 WP_266769921.1 hypothetical protein -
  OHU11_RS20255 (OHU11_20235) - 4546332..4546928 (-) 597 WP_266689459.1 ankyrin repeat domain-containing protein -
  OHU11_RS20260 (OHU11_20240) - 4546974..4547531 (-) 558 WP_266689461.1 heme-binding protein -
  OHU11_RS20265 (OHU11_20245) - 4547817..4549148 (+) 1332 WP_266689463.1 sensor histidine kinase -
  OHU11_RS20270 (OHU11_20250) vraR 4549145..4549774 (+) 630 WP_266689464.1 response regulator transcription factor Regulator
  OHU11_RS20275 (OHU11_20255) - 4549894..4550391 (+) 498 WP_124717226.1 hypothetical protein -
  OHU11_RS20280 (OHU11_20260) - 4550431..4551123 (-) 693 WP_266693711.1 pentapeptide repeat-containing protein -
  OHU11_RS20285 (OHU11_20265) - 4551187..4551681 (-) 495 WP_266689466.1 GNAT family N-acetyltransferase -
  OHU11_RS20290 (OHU11_20270) - 4551777..4552460 (+) 684 WP_266689468.1 rhomboid-like protein -
  OHU11_RS20295 (OHU11_20275) - 4552571..4553971 (+) 1401 WP_266689469.1 FAD-dependent oxidoreductase -
  OHU11_RS20300 (OHU11_20280) - 4554321..4554548 (+) 228 WP_266689471.1 hypothetical protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 22127.52 Da        Isoelectric Point: 5.1031

>NTDB_id=653110 OHU11_RS20270 WP_266689464.1 4549145..4549774(+) (vraR) [Streptomyces sp. NBC_00257]
MTASPTVRILLCDDHVVVRAGLLALLGSEPDIEVVGEAGSGEEAVALAAKLTPDVVLMDLQLGEGIDGVEATRRIAATGV
HVLVLTTYDTDADITRAIEAGATGYLLKAERPEELFAAIRSAAQGRTTLSPPVASRVMARMRKPLPTLTDRELDILAQLS
QGLGNRDIARALFISEATVKTHLGRIYDKLGVDTRAGAVAVAKEQRLLP

Nucleotide


Download         Length: 630 bp        

>NTDB_id=653110 OHU11_RS20270 WP_266689464.1 4549145..4549774(+) (vraR) [Streptomyces sp. NBC_00257]
ATGACCGCGTCGCCGACCGTACGCATCCTGCTCTGCGACGACCACGTCGTCGTACGCGCCGGTCTCCTCGCCCTCCTCGG
CAGCGAACCGGACATCGAGGTCGTAGGCGAGGCCGGCAGCGGCGAGGAGGCGGTCGCCCTGGCCGCCAAGCTCACCCCGG
ACGTCGTCCTGATGGACCTCCAGCTCGGCGAGGGCATCGACGGCGTGGAGGCCACCCGCCGCATCGCCGCCACCGGCGTC
CACGTGCTGGTCCTCACCACGTACGACACGGACGCCGACATCACCCGGGCCATCGAGGCGGGCGCCACCGGCTATCTGCT
GAAGGCCGAGCGCCCCGAGGAGCTATTCGCCGCGATCCGCTCGGCGGCCCAGGGCCGTACGACGCTCTCCCCGCCGGTGG
CCAGCCGGGTCATGGCCCGGATGCGCAAGCCCCTGCCCACCCTCACCGACCGCGAGCTCGACATCCTGGCCCAGCTCTCC
CAGGGCCTGGGCAACCGCGACATCGCCCGCGCCCTGTTCATCAGCGAGGCCACGGTCAAGACCCACCTCGGCCGGATCTA
CGACAAGCTCGGCGTCGACACCCGGGCGGGCGCCGTGGCCGTGGCGAAGGAGCAGCGGCTGCTGCCGTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(9-120)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.385

99.522

0.402
  degU Bacillus subtilis subsp. subtilis str. 168

35.78

100

0.373