Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHU11_RS12445 Genome accession   NZ_CP108082
Coordinates   2793955..2794620 (-) Length   221 a.a.
NCBI ID   WP_124720973.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00257     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2788955..2799620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHU11_RS12425 (OHU11_12400) - 2789307..2790971 (+) 1665 WP_266769002.1 sensor histidine kinase -
  OHU11_RS12430 (OHU11_12405) - 2790968..2791651 (+) 684 WP_266688191.1 response regulator -
  OHU11_RS12435 (OHU11_12410) - 2791779..2793371 (-) 1593 WP_266688192.1 cation acetate symporter -
  OHU11_RS12440 (OHU11_12415) - 2793368..2793811 (-) 444 WP_266772604.1 DUF485 domain-containing protein -
  OHU11_RS12445 (OHU11_12420) vraR 2793955..2794620 (-) 666 WP_124720973.1 response regulator transcription factor Regulator
  OHU11_RS12450 (OHU11_12425) - 2794617..2795783 (-) 1167 WP_266769005.1 histidine kinase -
  OHU11_RS12455 (OHU11_12430) - 2795780..2796388 (-) 609 WP_266769007.1 DUF1453 domain-containing protein -
  OHU11_RS12460 (OHU11_12435) - 2796516..2798636 (-) 2121 WP_266688195.1 DNA topoisomerase IV subunit B -
  OHU11_RS12465 (OHU11_12440) - 2799072..2799305 (+) 234 WP_024489001.1 hypothetical protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23506.98 Da        Isoelectric Point: 4.8161

>NTDB_id=653088 OHU11_RS12445 WP_124720973.1 2793955..2794620(-) (vraR) [Streptomyces sp. NBC_00257]
MNARVVVADDQSVVREGIVMLLGLLPGIEVVGSAKDGEEAVELVAELAPDVVLMDLRMPRCDGAEATRRIRRDHPGTQVV
VLTTFADDDSLFPALQAGARGYLTKDAGGEEIVRAIQAVLSGEAGLSPSVQRRLLERVTAGPPPLPTAPEPQLPDGLTPR
ELEVLVLIAEGLSNLEIARSLNISQATVKSHINNLFAKAGVRDRAQAVRYAYVRGLAQPPG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=653088 OHU11_RS12445 WP_124720973.1 2793955..2794620(-) (vraR) [Streptomyces sp. NBC_00257]
GTGAACGCACGGGTCGTGGTCGCCGACGACCAGTCGGTGGTGCGTGAGGGGATTGTGATGCTGCTGGGGCTGCTGCCCGG
AATCGAGGTCGTCGGGTCGGCGAAGGACGGGGAGGAGGCCGTGGAGCTCGTGGCCGAACTGGCCCCCGATGTCGTTCTGA
TGGACCTGCGGATGCCCCGGTGCGACGGGGCGGAGGCGACACGGCGGATCCGCAGGGACCATCCGGGGACCCAGGTGGTG
GTGCTCACGACTTTCGCGGACGACGACTCGCTCTTCCCCGCGCTGCAGGCCGGAGCCCGCGGCTATCTCACCAAGGACGC
CGGGGGCGAGGAGATCGTACGGGCCATCCAGGCCGTGCTGTCCGGCGAGGCCGGCCTCTCGCCGAGTGTGCAGCGTCGTC
TGCTGGAGCGCGTGACCGCGGGCCCGCCACCGCTCCCGACGGCACCGGAGCCACAGCTGCCCGACGGTCTGACGCCACGT
GAGCTGGAGGTGCTGGTGCTGATCGCGGAGGGCCTGTCCAATCTGGAGATCGCCCGCAGCCTGAACATCTCGCAGGCCAC
CGTGAAGAGCCACATCAACAACCTCTTCGCCAAGGCCGGAGTACGCGACCGGGCACAGGCCGTTCGCTACGCGTATGTTC
GGGGCCTCGCACAGCCGCCCGGATGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(156-211)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.991

98.643

0.385
  degU Bacillus subtilis subsp. subtilis str. 168

37.838

100

0.38