Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG718_RS49715 Genome accession   NZ_CP108081
Coordinates   11227497..11228183 (+) Length   228 a.a.
NCBI ID   WP_143642157.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00258     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 11222497..11233183
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG718_RS49700 (OG718_49700) - 11223210..11225435 (-) 2226 WP_186001397.1 MMPL family transporter -
  OG718_RS49705 (OG718_49705) - 11225568..11226143 (-) 576 WP_143642161.1 SAM-dependent methyltransferase -
  OG718_RS49710 (OG718_49710) - 11226325..11227500 (+) 1176 WP_328847330.1 sensor histidine kinase -
  OG718_RS49715 (OG718_49715) vraR 11227497..11228183 (+) 687 WP_143642157.1 response regulator transcription factor Regulator
  OG718_RS49720 (OG718_49720) - 11228220..11228816 (-) 597 WP_143642155.1 TetR/AcrR family transcriptional regulator -
  OG718_RS49725 (OG718_49725) - 11228952..11229410 (+) 459 WP_143642154.1 cupin domain-containing protein -
  OG718_RS49730 (OG718_49730) - 11229457..11230266 (+) 810 WP_143642152.1 alpha/beta hydrolase -
  OG718_RS49735 (OG718_49735) - 11230320..11230802 (-) 483 WP_328847331.1 DUF4259 domain-containing protein -
  OG718_RS49740 (OG718_49740) - 11230995..11232017 (-) 1023 WP_328847972.1 GNAT family N-acetyltransferase -
  OG718_RS49745 (OG718_49745) - 11232063..11232249 (-) 187 Protein_9854 ATP-binding protein -
  OG718_RS49750 (OG718_49750) - 11232200..11233138 (-) 939 WP_223064972.1 DUF4184 family protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 24591.35 Da        Isoelectric Point: 6.0286

>NTDB_id=653067 OG718_RS49715 WP_143642157.1 11227497..11228183(+) (vraR) [Streptomyces sp. NBC_00258]
MIRVLVVDDQTLVRAGVTLLLRTAGENVVGEATDGLEAVRMAERLRPDVILMDLRMPRVDGIEATRRILKTLPATRIVML
TTFDDDAEVYGALRAGAVGYLLKDGEPDAMLSAVRRAAQGESLLAPAVMARVVRRAVQSHHQDVTGDTADPAILATLTPR
ERDVLALVGVGQSNAEIAESLHLGVTTVKTHVASVTDKLRLRNRVQAAVVAHRLGLVDDDFRLAEGPE

Nucleotide


Download         Length: 687 bp        

>NTDB_id=653067 OG718_RS49715 WP_143642157.1 11227497..11228183(+) (vraR) [Streptomyces sp. NBC_00258]
ATGATCCGCGTACTCGTCGTCGACGACCAGACCCTCGTACGCGCCGGGGTCACCCTCCTGCTGCGTACAGCGGGGGAGAA
CGTGGTCGGCGAAGCCACGGACGGACTCGAAGCCGTACGCATGGCCGAGCGGCTGCGCCCGGACGTCATCCTCATGGACC
TGCGCATGCCACGGGTGGACGGAATCGAGGCCACTCGCCGCATCCTCAAGACCCTCCCGGCAACGCGCATCGTGATGCTC
ACGACCTTCGACGACGACGCCGAGGTCTACGGTGCCCTGCGCGCCGGGGCCGTCGGCTATCTGCTGAAGGACGGCGAACC
CGACGCGATGCTGTCCGCCGTACGGCGGGCCGCGCAGGGCGAGTCGCTCCTTGCTCCCGCGGTCATGGCGCGCGTCGTCC
GGCGCGCCGTCCAGTCACACCACCAGGACGTCACCGGCGACACGGCCGATCCGGCGATTCTGGCAACACTCACACCCCGC
GAACGAGACGTACTCGCCCTCGTCGGCGTCGGACAGTCCAACGCCGAGATCGCCGAGAGCCTTCACCTCGGCGTGACCAC
GGTCAAGACCCACGTCGCCTCCGTCACGGACAAACTGCGACTGCGCAACCGCGTCCAGGCCGCTGTCGTGGCCCACCGAC
TGGGCCTGGTCGACGACGACTTCCGTCTCGCCGAGGGCCCCGAATAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-114)

Bacterial regulatory proteins, luxR family (GerE)

(156-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.092

95.175

0.382
  degU Bacillus subtilis subsp. subtilis str. 168

37.611

99.123

0.373