Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG718_RS45745 Genome accession   NZ_CP108081
Coordinates   10311778..10312443 (+) Length   221 a.a.
NCBI ID   WP_143633302.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00258     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 10306778..10317443
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG718_RS45730 (OG718_45730) - 10307269..10308099 (-) 831 WP_143633299.1 AfsR/SARP family transcriptional regulator -
  OG718_RS45735 (OG718_45735) - 10308084..10310405 (+) 2322 WP_328846925.1 MMPL family transporter -
  OG718_RS45740 (OG718_45740) - 10310450..10311781 (+) 1332 WP_328846926.1 sensor histidine kinase -
  OG718_RS45745 (OG718_45745) vraR 10311778..10312443 (+) 666 WP_143633302.1 response regulator transcription factor Regulator
  OG718_RS45750 (OG718_45750) - 10312404..10312688 (-) 285 WP_143633304.1 DUF6332 family protein -
  OG718_RS45755 (OG718_45755) - 10312835..10314343 (-) 1509 WP_328846927.1 MFS transporter -
  OG718_RS45760 (OG718_45760) - 10314430..10314840 (+) 411 WP_328846928.1 MarR family transcriptional regulator -
  OG718_RS45765 (OG718_45765) - 10314898..10315635 (-) 738 WP_328846930.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OG718_RS45770 (OG718_45770) - 10316047..10316946 (-) 900 WP_143633310.1 NAD(P)-dependent oxidoreductase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24010.68 Da        Isoelectric Point: 4.7221

>NTDB_id=653054 OG718_RS45745 WP_143633302.1 10311778..10312443(+) (vraR) [Streptomyces sp. NBC_00258]
MIRVLLADDQSLVRAGFKALLDAQPDIEVAGEAADGEEALRAVRELRPDVVLMDIRMPRLDGLAATRRITDDNGLNDVRV
VMLTTFELDEYVFEAIRAGASGFLVKDTEPEELLRAVRAVVEGDALLSPGVTRRLIAEFAARSKEPAAAGALAELTERER
EVMALVGIGLSNDEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=653054 OG718_RS45745 WP_143633302.1 10311778..10312443(+) (vraR) [Streptomyces sp. NBC_00258]
GTGATCCGCGTACTGCTCGCCGACGACCAGTCACTGGTCCGCGCAGGCTTCAAGGCACTTCTCGACGCCCAGCCGGACAT
CGAGGTGGCCGGAGAGGCCGCCGACGGTGAGGAGGCGCTGCGTGCGGTACGCGAACTGCGGCCCGACGTCGTCCTGATGG
ACATCCGCATGCCCCGGCTCGACGGCCTCGCCGCGACCCGCCGCATCACCGACGACAACGGCCTGAATGACGTCAGGGTC
GTCATGCTCACCACCTTCGAGCTGGACGAGTACGTCTTCGAGGCCATCCGCGCCGGAGCGTCCGGCTTCCTCGTCAAGGA
CACCGAACCGGAGGAACTCCTGCGCGCTGTGCGGGCGGTGGTCGAGGGCGACGCACTGCTGTCACCGGGTGTGACCCGTC
GGCTCATCGCCGAGTTCGCGGCGCGCTCCAAGGAGCCCGCGGCCGCCGGCGCGCTCGCCGAACTCACCGAGCGGGAGCGG
GAGGTGATGGCGCTGGTCGGCATCGGACTGTCGAACGACGAGATCGCGCGCCGACTGGTCGTCAGCCCGTTGACCGCCAA
GACCCACGTCAGCCGGACCATGGTGAAGCTGGGTGCCCGCGACCGGGCCCAACTGGTCGTGCTCGCCTACGAGTCGGGGC
TGGTGCGGCCGGGCTGGCTGGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(155-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.14

97.285

0.371
  degU Bacillus subtilis subsp. subtilis str. 168

36.444

100

0.371