Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG718_RS44155 Genome accession   NZ_CP108081
Coordinates   9919469..9920131 (-) Length   220 a.a.
NCBI ID   WP_143644232.1    Uniprot ID   A0ABZ1HQC1
Organism   Streptomyces sp. NBC_00258     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 9914469..9925131
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG718_RS44135 (OG718_44125) - 9915200..9916030 (-) 831 WP_143644229.1 alpha/beta fold hydrolase -
  OG718_RS44140 (OG718_44130) - 9916244..9917128 (+) 885 WP_143644230.1 RNA polymerase sigma-70 factor -
  OG718_RS44145 (OG718_44135) - 9917372..9918133 (+) 762 WP_143644246.1 GntR family transcriptional regulator -
  OG718_RS44150 (OG718_44140) - 9918210..9919367 (-) 1158 WP_143644231.1 ROK family transcriptional regulator -
  OG718_RS44155 (OG718_44145) vraR 9919469..9920131 (-) 663 WP_143644232.1 response regulator transcription factor Regulator
  OG718_RS44160 (OG718_44150) - 9920146..9921300 (-) 1155 WP_328846797.1 histidine kinase -
  OG718_RS44165 (OG718_44155) - 9921409..9922347 (+) 939 WP_328846798.1 ATP-binding cassette domain-containing protein -
  OG718_RS44170 (OG718_44160) - 9922350..9923075 (+) 726 WP_143644235.1 ABC transporter permease -
  OG718_RS44175 (OG718_44165) - 9923141..9923587 (+) 447 WP_306941140.1 hypothetical protein -
  OG718_RS44180 (OG718_44170) mug 9923619..9924164 (-) 546 WP_328847933.1 G/U mismatch-specific DNA glycosylase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23355.92 Da        Isoelectric Point: 4.7315

>NTDB_id=653050 OG718_RS44155 WP_143644232.1 9919469..9920131(-) (vraR) [Streptomyces sp. NBC_00258]
MPVTVLLVDDEPLVRAGLRAVLEAQPDIEVVGEAADGAAVIPLVRQLRPDVVAMDVRMPLLDGIEATRAVLRTVDNPPKI
LVVTTFENDEYVYEALRAGADGFLLKRARPAEIVNAVRLVAEGESLLFPASVRQLAAEYGVGGGNPAARAALDRAALTER
EAEVLRLMTRGLSNAEIATRLIVGTETVKSHVSSVLAKLGARDRTQAVIAAYESGFVAPG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=653050 OG718_RS44155 WP_143644232.1 9919469..9920131(-) (vraR) [Streptomyces sp. NBC_00258]
GTGCCGGTCACCGTTCTGCTTGTCGACGACGAACCCCTCGTACGCGCGGGTCTACGCGCCGTTCTGGAGGCGCAGCCCGA
CATCGAGGTCGTCGGGGAGGCGGCCGACGGTGCAGCAGTCATCCCGCTGGTCCGGCAGTTGCGGCCCGATGTCGTCGCGA
TGGACGTCCGTATGCCGCTCCTGGACGGCATCGAGGCCACGCGCGCGGTGCTGCGGACGGTCGACAACCCGCCGAAGATC
CTCGTGGTGACGACCTTCGAGAACGACGAGTACGTGTACGAGGCGCTGCGCGCGGGTGCCGACGGTTTCCTGCTCAAGCG
GGCGCGGCCGGCCGAGATCGTGAACGCGGTGCGGCTGGTCGCCGAGGGCGAGTCGCTGCTGTTCCCGGCTTCGGTACGGC
AGTTGGCCGCCGAGTACGGGGTCGGCGGCGGGAATCCCGCGGCCCGGGCCGCGCTGGACCGGGCGGCCCTGACCGAGCGC
GAGGCGGAGGTTCTCCGGCTGATGACCCGGGGTCTGTCGAACGCGGAGATCGCCACGCGGTTGATCGTGGGTACCGAGAC
GGTGAAGTCCCACGTCAGCTCCGTACTGGCGAAGCTGGGGGCGCGGGACCGTACGCAGGCGGTGATCGCGGCGTACGAGT
CGGGGTTCGTGGCGCCCGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(156-210)

Response regulator receiver domain (Response_reg)

(5-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.743

99.091

0.414
  degU Bacillus subtilis subsp. subtilis str. 168

36.726

100

0.377