Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG718_RS13745 Genome accession   NZ_CP108081
Coordinates   3047065..3047733 (+) Length   222 a.a.
NCBI ID   WP_328844258.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00258     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3042065..3052733
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG718_RS13715 (OG718_13710) - 3042266..3042766 (-) 501 WP_306936562.1 PaaI family thioesterase -
  OG718_RS13720 (OG718_13715) - 3042860..3043327 (+) 468 WP_328844256.1 helix-turn-helix domain-containing protein -
  OG718_RS13725 (OG718_13720) - 3043446..3044384 (-) 939 WP_143640852.1 RNA polymerase sigma-70 factor -
  OG718_RS13730 (OG718_13725) - 3044561..3045046 (+) 486 WP_143640853.1 carboxymuconolactone decarboxylase family protein -
  OG718_RS13735 (OG718_13730) - 3045218..3045790 (+) 573 WP_328847756.1 TetR/AcrR family transcriptional regulator -
  OG718_RS13740 (OG718_13735) - 3045905..3047068 (+) 1164 WP_328844257.1 sensor histidine kinase -
  OG718_RS13745 (OG718_13740) vraR 3047065..3047733 (+) 669 WP_328844258.1 response regulator transcription factor Regulator
  OG718_RS13750 (OG718_13745) - 3047882..3048097 (+) 216 WP_143640856.1 hypothetical protein -
  OG718_RS13755 (OG718_13750) - 3048104..3050287 (+) 2184 WP_328844259.1 MMPL family transporter -
  OG718_RS13760 (OG718_13755) - 3050479..3051345 (-) 867 WP_328844260.1 alpha/beta hydrolase -
  OG718_RS13765 (OG718_13760) - 3051662..3052666 (+) 1005 WP_143640858.1 NADP-dependent oxidoreductase -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 24092.60 Da        Isoelectric Point: 4.7045

>NTDB_id=652969 OG718_RS13745 WP_328844258.1 3047065..3047733(+) (vraR) [Streptomyces sp. NBC_00258]
MIRVLLADDQRLVRAGFRSILEDHDDIEVVGEAADGEAAVAACRELRPDVVLMDIRMPGTDGLEAAREIAGDEQLASVKV
VILTTFDLDDYVYGALRAGTTGFLVKDTEPEELLQAVRVAARGDALISPSVTRRLIAEFAGRVKGPRPDPRLDALTERER
EVMRLVAAGLTNDEIAARLVLSPSTAKTHVSRIMSKLGARDRSQVVVLAYESGMVSPGWMAQ

Nucleotide


Download         Length: 669 bp        

>NTDB_id=652969 OG718_RS13745 WP_328844258.1 3047065..3047733(+) (vraR) [Streptomyces sp. NBC_00258]
ATGATCAGGGTCCTGCTGGCGGACGACCAGCGGCTCGTCCGGGCCGGTTTCCGGTCGATCCTGGAGGACCACGACGACAT
CGAGGTGGTGGGCGAGGCAGCGGACGGCGAGGCCGCGGTCGCCGCCTGCCGCGAGCTCCGGCCTGACGTGGTCCTGATGG
ACATCAGAATGCCGGGGACGGACGGTCTGGAAGCCGCCCGGGAGATCGCCGGGGACGAGCAGTTGGCGTCGGTCAAGGTG
GTCATCCTGACGACCTTCGATCTGGACGACTACGTGTACGGGGCGCTGCGCGCCGGCACGACGGGCTTTCTGGTGAAGGA
CACGGAGCCGGAGGAACTGCTGCAGGCGGTACGGGTCGCCGCCCGGGGTGATGCCCTGATCAGCCCCTCGGTCACGCGGC
GGCTCATCGCCGAGTTCGCGGGCCGGGTGAAGGGCCCTCGGCCGGATCCCCGGCTCGACGCTCTCACCGAGCGGGAACGC
GAGGTCATGCGGCTGGTGGCCGCAGGGCTCACGAACGACGAGATCGCTGCGCGGCTGGTGCTGTCACCGTCCACGGCCAA
GACGCATGTCAGCCGGATCATGTCGAAGCTGGGGGCGCGGGACAGATCTCAGGTCGTGGTGCTGGCGTACGAGTCCGGAA
TGGTCAGTCCCGGCTGGATGGCGCAATAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-118)

Bacterial regulatory proteins, luxR family (GerE)

(154-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.187

96.396

0.387
  degU Bacillus subtilis subsp. subtilis str. 168

37.333

100

0.378