Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG766_RS29395 Genome accession   NZ_CP108080
Coordinates   6549144..6549815 (+) Length   223 a.a.
NCBI ID   WP_266387013.1    Uniprot ID   A0ACC6QQP8
Organism   Streptomyces sp. NBC_00259     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6544144..6554815
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG766_RS29370 (OG766_29360) - 6544378..6545259 (+) 882 WP_266387023.1 YegS/Rv2252/BmrU family lipid kinase -
  OG766_RS29375 (OG766_29365) - 6545338..6546579 (-) 1242 WP_266387021.1 saccharopine dehydrogenase C-terminal domain-containing protein -
  OG766_RS29380 (OG766_29370) - 6546684..6547385 (+) 702 WP_266387019.1 TetR/AcrR family transcriptional regulator -
  OG766_RS29385 (OG766_29375) - 6547546..6547770 (-) 225 WP_266387017.1 hypothetical protein -
  OG766_RS29390 (OG766_29380) - 6547918..6549147 (+) 1230 WP_266387015.1 histidine kinase -
  OG766_RS29395 (OG766_29385) vraR 6549144..6549815 (+) 672 WP_266387013.1 response regulator transcription factor Regulator
  OG766_RS29400 (OG766_29390) - 6550032..6551036 (-) 1005 WP_266387011.1 Gfo/Idh/MocA family oxidoreductase -
  OG766_RS29405 (OG766_29395) - 6551174..6551911 (+) 738 WP_266388756.1 GntR family transcriptional regulator -
  OG766_RS29410 (OG766_29400) - 6552081..6553076 (+) 996 WP_266387009.1 sugar ABC transporter substrate-binding protein -
  OG766_RS29415 (OG766_29405) - 6553184..6554197 (+) 1014 WP_266387007.1 sugar ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 23742.27 Da        Isoelectric Point: 5.3662

>NTDB_id=652944 OG766_RS29395 WP_266387013.1 6549144..6549815(+) (vraR) [Streptomyces sp. NBC_00259]
MTIRVLIVDDDPLVRAGLTFMLGGAEDIEIVGEGADGDEATDLTERLRPDVVLMDIRMPRVDGLTATERLRARPDAPEVV
VLTTFHADEQVLRALRAGAAGFVLKDTPPTEIVAAVRRVATGEPVLSPAVTRQLMTHVAGAAPDDRPGRARARLGTLAER
EREVAVAVGRGHSNAEIAASLYMSVPTVKTHVSRILAKLGLNNRVQIALLVHDAGMLDEGAAS

Nucleotide


Download         Length: 672 bp        

>NTDB_id=652944 OG766_RS29395 WP_266387013.1 6549144..6549815(+) (vraR) [Streptomyces sp. NBC_00259]
ATGACCATCCGGGTGCTCATCGTCGACGACGACCCCCTCGTGCGCGCAGGACTCACTTTCATGCTCGGCGGGGCGGAGGA
CATCGAGATCGTGGGGGAGGGCGCCGACGGCGACGAAGCCACCGACCTCACCGAACGGCTGCGGCCCGACGTCGTCCTCA
TGGACATCCGGATGCCGCGCGTGGACGGGCTCACCGCCACCGAACGGCTCCGGGCCCGCCCCGACGCACCCGAGGTCGTG
GTCCTCACCACCTTCCACGCCGACGAGCAGGTGCTGCGCGCGCTGCGGGCCGGCGCCGCGGGCTTCGTCCTCAAGGACAC
CCCGCCCACCGAGATCGTCGCCGCCGTACGACGGGTGGCGACCGGCGAACCGGTGCTCTCGCCCGCCGTCACCCGCCAGC
TCATGACGCATGTCGCGGGCGCCGCCCCCGACGACCGGCCCGGCCGCGCCCGCGCCCGCCTCGGCACCCTCGCCGAACGG
GAACGCGAGGTCGCCGTCGCGGTCGGCCGCGGCCACTCCAACGCCGAGATCGCCGCGAGCCTCTACATGAGCGTGCCGAC
CGTGAAGACCCATGTGTCCCGCATCCTCGCCAAACTCGGCCTCAACAACCGGGTCCAGATCGCGCTGCTGGTCCATGACG
CGGGGATGCTGGACGAGGGGGCGGCCTCGTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(156-210)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.58

92.825

0.377
  degU Bacillus subtilis subsp. subtilis str. 168

36.607

100

0.368