Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG766_RS10755 Genome accession   NZ_CP108080
Coordinates   2393182..2393862 (+) Length   226 a.a.
NCBI ID   WP_328725158.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00259     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2388182..2398862
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG766_RS10735 (OG766_10735) - 2388714..2389400 (+) 687 WP_266374422.1 TetR family transcriptional regulator -
  OG766_RS10740 (OG766_10740) - 2389488..2390699 (+) 1212 WP_328725157.1 alpha/beta hydrolase -
  OG766_RS10745 (OG766_10745) - 2390786..2391649 (+) 864 WP_266374420.1 DUF4429 domain-containing protein -
  OG766_RS10750 (OG766_10750) - 2391815..2393185 (+) 1371 WP_266374419.1 sensor histidine kinase -
  OG766_RS10755 (OG766_10755) vraR 2393182..2393862 (+) 681 WP_328725158.1 response regulator transcription factor Regulator
  OG766_RS10760 (OG766_10760) - 2393967..2395022 (+) 1056 WP_266374417.1 alpha/beta hydrolase -
  OG766_RS10765 (OG766_10765) - 2395019..2396239 (+) 1221 WP_328725160.1 acyltransferase -
  OG766_RS10770 (OG766_10770) - 2396308..2397318 (-) 1011 WP_266374415.1 aldo/keto reductase -
  OG766_RS10775 (OG766_10775) - 2397323..2397778 (-) 456 WP_266374414.1 MerR family transcriptional regulator -
  OG766_RS10780 (OG766_10780) - 2397901..2398365 (+) 465 WP_266374413.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24172.05 Da        Isoelectric Point: 5.6117

>NTDB_id=652889 OG766_RS10755 WP_328725158.1 2393182..2393862(+) (vraR) [Streptomyces sp. NBC_00259]
MTIRVIIVDDQAMVRAGFAALLSAQADIDVVGEAPDGRQGVDLAHSAHPDVVLMDVRMPELDGLAAARQILTPPPGIVHV
PKVLMLTTFDIDDYVYEALRAGASGFLLKDAPPADLISAVRIVAAGEALLAPSVTRRLIADLVDKRPAPRKDRAALRLGG
LTPRETEVLELIARGLSNQEIAEHLVLAEQTVKTHIGRILAKLGLRDRAQAVIFAYESGLVTPGDH

Nucleotide


Download         Length: 681 bp        

>NTDB_id=652889 OG766_RS10755 WP_328725158.1 2393182..2393862(+) (vraR) [Streptomyces sp. NBC_00259]
TTGACCATCCGCGTGATCATCGTCGACGACCAGGCCATGGTGCGCGCGGGCTTCGCCGCCTTGCTGTCCGCCCAGGCGGA
CATCGACGTCGTCGGCGAGGCACCGGACGGACGGCAGGGTGTGGACCTGGCGCACTCGGCTCACCCCGATGTGGTGCTGA
TGGACGTGCGGATGCCGGAGCTGGACGGGCTGGCGGCGGCCCGGCAGATCCTGACCCCGCCGCCGGGGATCGTCCACGTG
CCGAAGGTGCTGATGCTGACGACCTTCGACATCGACGACTACGTGTACGAGGCGCTGCGCGCCGGGGCGTCCGGCTTTCT
GCTGAAGGACGCGCCGCCCGCCGATCTGATCTCGGCGGTACGGATCGTGGCCGCGGGCGAGGCCCTGCTCGCGCCCTCCG
TGACCCGTCGCCTGATCGCCGACCTCGTCGACAAGCGCCCGGCCCCGCGCAAGGACCGGGCCGCCCTGCGCCTGGGCGGC
CTCACCCCGCGCGAGACCGAGGTCCTGGAGCTGATCGCACGCGGCCTGTCCAACCAGGAGATCGCCGAGCATCTCGTCCT
CGCCGAGCAGACCGTGAAGACCCACATCGGCCGCATCCTCGCCAAGCTCGGCCTGCGCGACCGCGCGCAAGCGGTGATCT
TCGCGTACGAGTCCGGCCTCGTGACCCCTGGAGACCACTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-121)

Bacterial regulatory proteins, luxR family (GerE)

(161-215)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.249

97.788

0.442
  degU Bacillus subtilis subsp. subtilis str. 168

37.004

100

0.372