Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG766_RS03735 Genome accession   NZ_CP108080
Coordinates   842559..843224 (-) Length   221 a.a.
NCBI ID   WP_266376370.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00259     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 837559..848224
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG766_RS03710 (OG766_03700) - 838872..839222 (+) 351 WP_266376380.1 hypothetical protein -
  OG766_RS03715 (OG766_03705) - 839263..840003 (+) 741 WP_266376379.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OG766_RS03720 (OG766_03710) - 840153..840554 (-) 402 WP_266376377.1 MarR family transcriptional regulator -
  OG766_RS03725 (OG766_03715) - 840642..842159 (+) 1518 WP_266376375.1 MFS transporter -
  OG766_RS03730 (OG766_03720) - 842305..842598 (+) 294 WP_266376372.1 DUF6332 family protein -
  OG766_RS03735 (OG766_03725) vraR 842559..843224 (-) 666 WP_266376370.1 response regulator transcription factor Regulator
  OG766_RS03740 (OG766_03730) - 843322..844404 (-) 1083 WP_266378293.1 sensor histidine kinase -
  OG766_RS03745 (OG766_03735) - 844656..845420 (-) 765 WP_266376368.1 TetR/AcrR family transcriptional regulator -
  OG766_RS03750 (OG766_03740) - 845563..846018 (+) 456 WP_266376365.1 nitroreductase/quinone reductase family protein -
  OG766_RS03755 (OG766_03745) - 846008..847312 (-) 1305 WP_266378290.1 geranylgeranyl reductase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23899.53 Da        Isoelectric Point: 4.4673

>NTDB_id=652876 OG766_RS03735 WP_266376370.1 842559..843224(-) (vraR) [Streptomyces sp. NBC_00259]
MIRVLLADDQSLVRAGFRALLDAQPDIEVAGEAADGEEAVRNVAELRPDVVLMDIRMPLLDGLAATRRITEDAALEGVKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPEELLRAVRAVVDGDALLSPGVTRRLIAEFAARSKEPAGAEALAELTERER
EVMALVGIGLSNEEIARQLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=652876 OG766_RS03735 WP_266376370.1 842559..843224(-) (vraR) [Streptomyces sp. NBC_00259]
GTGATCCGGGTACTGCTCGCCGATGACCAGTCGCTCGTACGGGCCGGCTTCCGGGCGCTGCTCGACGCCCAGCCGGACAT
CGAGGTCGCCGGCGAGGCCGCGGACGGCGAGGAGGCGGTGCGCAACGTCGCCGAACTCAGGCCGGACGTCGTGCTGATGG
ACATCCGCATGCCGCTCCTCGATGGACTCGCCGCCACGCGGCGCATCACCGAGGACGCGGCGCTGGAGGGCGTGAAGGTC
GTCATGCTGACCACCTTCGAGCTGGACGAGTACGTCTTCGAGGCCATCCGCTCGGGAGCGTCCGGGTTCCTGGTGAAGGA
CACCGAGCCCGAGGAACTGCTCCGCGCGGTACGGGCGGTGGTGGACGGCGACGCGCTCCTTTCGCCCGGGGTGACGCGCC
GGCTCATCGCCGAGTTCGCCGCCCGCTCCAAGGAACCCGCCGGGGCCGAGGCGCTCGCCGAACTCACGGAGCGCGAGCGG
GAGGTGATGGCCCTGGTGGGGATCGGGCTGTCGAACGAGGAGATCGCCCGCCAGCTCGTGGTCAGCCCGCTCACCGCGAA
GACGCACGTCAGCAGGACGATGGTGAAGCTCGGCGCGCGCGACCGGGCCCAACTGGTCGTGCTGGCCTATGAGTCCGGGC
TGGTGCGGCCCGGGTGGCTCGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(155-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.605

97.285

0.376
  degU Bacillus subtilis subsp. subtilis str. 168

36.444

100

0.371