Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA28_RS39715 Genome accession   NZ_CP108075
Coordinates   8735726..8736391 (+) Length   221 a.a.
NCBI ID   WP_326714341.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00269     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8730726..8741391
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA28_RS39695 (OHA28_39735) - 8731641..8732873 (+) 1233 WP_326716189.1 geranylgeranyl reductase family protein -
  OHA28_RS39700 (OHA28_39740) - 8732857..8733339 (-) 483 WP_326714338.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  OHA28_RS39705 (OHA28_39745) - 8733604..8734338 (+) 735 WP_326714339.1 TetR/AcrR family transcriptional regulator -
  OHA28_RS39710 (OHA28_39750) - 8734482..8735729 (+) 1248 WP_328755268.1 sensor histidine kinase -
  OHA28_RS39715 (OHA28_39755) vraR 8735726..8736391 (+) 666 WP_326714341.1 response regulator transcription factor Regulator
  OHA28_RS39720 (OHA28_39760) - 8736525..8738036 (-) 1512 WP_326714342.1 MFS transporter -
  OHA28_RS39725 (OHA28_39765) - 8738124..8738528 (+) 405 WP_326714343.1 MarR family transcriptional regulator -
  OHA28_RS39730 (OHA28_39770) - 8738560..8739291 (-) 732 WP_326714344.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OHA28_RS39735 (OHA28_39775) - 8739356..8740573 (-) 1218 WP_328755269.1 MFS transporter -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24038.82 Da        Isoelectric Point: 4.9005

>NTDB_id=652780 OHA28_RS39715 WP_326714341.1 8735726..8736391(+) (vraR) [Streptomyces sp. NBC_00269]
MIRVLLADDQSLVRAGFRALLDAQSDIEVVGEASDGDEAVRLVRELRPAVVLMDIRMPVLDGLAATRRISDDAALETVKV
VMLTTFELDEYVFEAIRAGASGFLVKDTEPEELLRAVRAVVHGDALLSPGVTRRLIVEFAARSKEPAAAESLGQLTERER
EVMALVGIGLSNEEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=652780 OHA28_RS39715 WP_326714341.1 8735726..8736391(+) (vraR) [Streptomyces sp. NBC_00269]
TTGATCCGCGTACTGCTCGCCGACGACCAGTCGCTCGTCCGCGCCGGATTCCGGGCGCTGCTCGACGCGCAGAGCGACAT
CGAGGTCGTGGGGGAGGCCTCCGACGGCGACGAGGCGGTGCGCCTCGTACGCGAACTGCGGCCCGCCGTCGTCCTGATGG
ACATCCGGATGCCGGTCCTCGACGGGCTCGCAGCGACCCGCCGCATCAGCGACGACGCCGCGCTGGAAACCGTGAAGGTG
GTCATGCTGACCACCTTCGAACTGGACGAGTACGTCTTCGAGGCGATCCGTGCCGGAGCGTCCGGGTTCCTCGTCAAGGA
CACCGAGCCCGAGGAACTGCTGCGCGCCGTGAGGGCGGTGGTGCACGGCGACGCGCTGCTCTCGCCGGGGGTGACCCGCC
GTCTGATCGTCGAGTTCGCGGCGCGCTCCAAGGAGCCCGCGGCGGCCGAGTCGCTCGGGCAGCTCACCGAGCGCGAGCGT
GAGGTGATGGCGCTGGTCGGCATCGGCCTGTCGAACGAGGAGATCGCCCGCCGCCTCGTCGTCAGCCCGCTCACCGCGAA
GACACATGTGAGCCGCACGATGGTGAAGCTCGGCGCGCGTGACCGGGCCCAACTGGTCGTCCTCGCCTACGAGTCCGGGC
TCGTGCGGCCCGGCTGGCTCGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(154-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.07

97.285

0.38
  degU Bacillus subtilis subsp. subtilis str. 168

36

100

0.367