Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA28_RS35105 Genome accession   NZ_CP108075
Coordinates   7743999..7744649 (-) Length   216 a.a.
NCBI ID   WP_326713634.1    Uniprot ID   A0ABV4SSK2
Organism   Streptomyces sp. NBC_00269     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7738999..7749649
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA28_RS35085 (OHA28_35115) - 7739326..7740123 (+) 798 WP_326713630.1 HAD family acid phosphatase -
  OHA28_RS35090 (OHA28_35120) - 7740231..7741634 (+) 1404 WP_326713631.1 NCS2 family permease -
  OHA28_RS35095 (OHA28_35125) - 7741663..7742364 (+) 702 WP_326713632.1 hypothetical protein -
  OHA28_RS35100 (OHA28_35130) - 7742417..7743880 (-) 1464 WP_326713633.1 penicillin-binding transpeptidase domain-containing protein -
  OHA28_RS35105 (OHA28_35135) vraR 7743999..7744649 (-) 651 WP_326713634.1 response regulator transcription factor Regulator
  OHA28_RS35110 (OHA28_35140) - 7744668..7745921 (-) 1254 WP_326713635.1 histidine kinase -
  OHA28_RS35115 (OHA28_35145) - 7745918..7746928 (-) 1011 WP_326713636.1 hypothetical protein -
  OHA28_RS35120 (OHA28_35150) - 7747029..7747802 (-) 774 WP_116502788.1 IclR family transcriptional regulator -
  OHA28_RS35125 (OHA28_35155) - 7747938..7749470 (+) 1533 WP_326713637.1 aldehyde dehydrogenase (NADP(+)) -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 22718.16 Da        Isoelectric Point: 5.7729

>NTDB_id=652768 OHA28_RS35105 WP_326713634.1 7743999..7744649(-) (vraR) [Streptomyces sp. NBC_00269]
MSAIRVVLADDERMVRTALRAILSAEDGIEVVGEAATGAEAVSVVRELAPDVVLMDVRMPEVDGIRATEQILGSTAAPPR
IVVVTTFENDAYVYEALRAGAAGFLLKRAEADALVQAVRLVAHTDSLLFPAAVRALAAEYGRAEPSAAAWVARLTGRESE
VLRHMAAGLTNAEIARRMGVGPATVKTHVAAVLAKTGARDRTQAVIAAYEGGFMKA

Nucleotide


Download         Length: 651 bp        

>NTDB_id=652768 OHA28_RS35105 WP_326713634.1 7743999..7744649(-) (vraR) [Streptomyces sp. NBC_00269]
ATGAGCGCGATCCGTGTCGTCCTCGCCGACGACGAGCGCATGGTGCGCACCGCCCTGCGCGCCATCCTGTCCGCCGAGGA
CGGCATCGAGGTCGTGGGCGAGGCCGCGACCGGCGCCGAGGCGGTGTCCGTGGTGCGCGAGCTGGCGCCCGACGTGGTCC
TCATGGACGTCCGGATGCCGGAGGTCGACGGCATCCGCGCCACGGAACAGATCCTCGGGTCGACGGCCGCGCCCCCGCGC
ATCGTCGTGGTCACCACCTTCGAGAACGACGCGTACGTGTACGAGGCGCTGCGCGCCGGGGCCGCGGGGTTCCTCCTCAA
ACGCGCCGAGGCGGACGCGCTCGTGCAGGCGGTGCGCCTGGTCGCACACACGGACTCCCTGCTGTTCCCCGCGGCCGTGC
GCGCCCTCGCCGCGGAGTACGGGCGCGCCGAGCCCTCGGCGGCCGCGTGGGTGGCGCGGCTCACGGGCCGTGAGAGCGAG
GTACTGCGGCACATGGCCGCGGGCCTGACCAACGCGGAGATCGCGCGGCGGATGGGGGTGGGCCCCGCCACGGTGAAGAC
GCATGTGGCGGCGGTCCTCGCGAAGACCGGGGCCCGGGACCGTACACAGGCCGTGATCGCGGCGTACGAGGGCGGCTTCA
TGAAGGCGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(154-207)

Response regulator receiver domain (Response_reg)

(6-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.208

98.148

0.375
  degU Bacillus subtilis subsp. subtilis str. 168

35.088

100

0.37