Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA28_RS32195 Genome accession   NZ_CP108075
Coordinates   7112634..7113311 (-) Length   225 a.a.
NCBI ID   WP_116502281.1    Uniprot ID   A0ABV4SJY5
Organism   Streptomyces sp. NBC_00269     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7107634..7118311
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA28_RS32175 (OHA28_32210) - 7108520..7108981 (+) 462 WP_326713176.1 MerR family transcriptional regulator -
  OHA28_RS32180 (OHA28_32215) - 7108987..7110033 (+) 1047 WP_326713177.1 aldo/keto reductase -
  OHA28_RS32185 (OHA28_32220) - 7110103..7111320 (-) 1218 WP_326713178.1 acyltransferase -
  OHA28_RS32190 (OHA28_32225) - 7111317..7112447 (-) 1131 WP_326713179.1 alpha/beta hydrolase -
  OHA28_RS32195 (OHA28_32230) vraR 7112634..7113311 (-) 678 WP_116502281.1 response regulator transcription factor Regulator
  OHA28_RS32200 (OHA28_32235) - 7113328..7114692 (-) 1365 WP_326713180.1 sensor histidine kinase -
  OHA28_RS32205 (OHA28_32240) - 7114880..7115746 (-) 867 WP_326716106.1 DUF4429 domain-containing protein -
  OHA28_RS32210 (OHA28_32245) - 7115814..7117022 (-) 1209 WP_326713181.1 alpha/beta hydrolase -
  OHA28_RS32215 (OHA28_32250) - 7117183..7117827 (-) 645 WP_326713182.1 TetR family transcriptional regulator -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 24317.10 Da        Isoelectric Point: 4.9741

>NTDB_id=652763 OHA28_RS32195 WP_116502281.1 7112634..7113311(-) (vraR) [Streptomyces sp. NBC_00269]
MTIRVIIVDDQAMVRAGFAALLAAQSDIDVVGEAPDGKQGVEVSRTTHPDVVLMDVRMPEMDGIAATRALLDPPPGVIHR
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLIAAVRVVAAGEALLAPTVTRRLIEDIARQRPSGRRDRSPELNCL
TPRETEVLELIARGLSNQEIAEKLVLAEQTVKTHIGRVLAKLGLRDRAQAVIFAYETGLVTPGDQ

Nucleotide


Download         Length: 678 bp        

>NTDB_id=652763 OHA28_RS32195 WP_116502281.1 7112634..7113311(-) (vraR) [Streptomyces sp. NBC_00269]
ATGACCATCCGCGTGATCATTGTCGACGACCAGGCCATGGTGCGAGCGGGGTTCGCCGCGCTGCTGGCCGCTCAGAGCGA
CATCGACGTCGTGGGCGAGGCTCCGGACGGCAAGCAGGGTGTCGAGGTCAGCCGGACGACACATCCCGATGTCGTCCTCA
TGGACGTGCGGATGCCCGAGATGGACGGGATCGCCGCGACCCGCGCGCTCCTCGACCCTCCACCGGGCGTGATCCACCGC
CCCAAGGTCCTGATGCTCACCACGTTCGACGTGGACGACTACGTGTACGAGGCCCTGCGCGCCGGCGCTTCGGGTTTCCT
CCTCAAGGACGCCCCGCCGGCCGATCTCATCGCGGCGGTGCGTGTGGTGGCCGCCGGAGAGGCGCTGCTCGCCCCGACGG
TCACACGCCGGCTCATCGAGGACATCGCGAGGCAGCGCCCGTCCGGCCGCAGGGACCGTTCGCCGGAGCTGAACTGCCTG
ACGCCACGCGAGACCGAGGTCCTCGAACTCATCGCCCGGGGCCTGTCCAACCAGGAGATCGCGGAGAAGCTGGTGCTCGC
GGAGCAGACCGTGAAGACCCATATCGGCCGCGTGCTCGCGAAGTTGGGGCTGCGAGACCGGGCGCAGGCCGTGATTTTCG
CCTACGAGACCGGTCTCGTCACGCCCGGCGACCAATAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-121)

Bacterial regulatory proteins, luxR family (GerE)

(159-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.273

97.778

0.413
  degU Bacillus subtilis subsp. subtilis str. 168

38.326

100

0.387