Detailed information NTG0652740

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OHA28_RS23355
• Genome accession: NZ_CP108075
• Coordinates: 5139076..5140200 (+)
• Length: 374 a.a.
• NCBI ID: WP_116511422.1
• Uniprot ID: A0ABV4SRP8
• Organism: Streptomyces sp. NBC_00269
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 5134076..5145200

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHA28_RS23340 (OHA28_23380)	-	5134606..5135535 (+)	930	WP_326711794.1	hypothetical protein	-
OHA28_RS23345 (OHA28_23385)	-	5135569..5137287 (-)	1719	WP_326711795.1	hypothetical protein	-
OHA28_RS23350 (OHA28_23390)	radA/sms	5137554..5138963 (+)	1410	WP_116511420.1	DNA repair protein RadA	Machinery gene
OHA28_RS23355 (OHA28_23395)	disA	5139076..5140200 (+)	1125	WP_116511422.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OHA28_RS23360 (OHA28_23400)	-	5140539..5141333 (-)	795	WP_326711796.1	hypothetical protein	-
OHA28_RS23365 (OHA28_23405)	-	5141519..5142160 (+)	642	WP_326711797.1	phosphatase PAP2 family protein	-
OHA28_RS23370 (OHA28_23410)	-	5142161..5142625 (-)	465	WP_326716010.1	response regulator transcription factor	-
OHA28_RS23375 (OHA28_23415)	-	5143424..5144320 (+)	897	WP_326711798.1	A/G-specific adenine glycosylase	-
OHA28_RS23380 (OHA28_23420)	-	5144502..5145050 (+)	549	WP_116511432.1	SigE family RNA polymerase sigma factor	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40297.15 Da
• Isoelectric Point: 4.9269

>NTDB_id=652740 OHA28_RS23355 WP_116511422.1 5139076..5140200(+) (disA) [Streptomyces sp. NBC_00269]
MAANDRAAAPGKSGGSSGADGLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGWDKTVESMCTGGFILDVEFTATRLR
ELCKLDGGIVIDKDITKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVSFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALFELDALTHAELLELPTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQAVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=652740 OHA28_RS23355 WP_116511422.1 5139076..5140200(+) (disA) [Streptomyces sp. NBC_00269]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGCAAGTCCGGCGGGAGCTCCGGTGCCGATGGGCTGATGCGCGCCTCACT
GAGCGCGGTCGCGCCCGGTACGGCGCTGCGTGACGGCCTCGAGCGAATCCTCCGCGGCAACACCGGCGGACTCATCGTTC
TCGGCTGGGACAAGACCGTCGAGTCGATGTGTACCGGCGGTTTCATCCTGGACGTCGAGTTCACCGCGACGCGTCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTCATCGACAAGGACATCACCAAGATCCTTCGGGCGGGCGTCCAGTTGGTGCC
CGACCCCACGATCCCCACGGAGGAGACGGGCACGCGGCACCGCACCGCGGACCGGGTGAGCAAGCAGGTCAGCTTCCCCG
TGGTCTCGGTGTCTCAGTCGATGCGGCTCATCGCCCTTTACGTGGACGGGCAGCGGCGCGTCCTCGAGGACTCGGCCGCG
ATTCTCTCGCGGGCGAATCAGGCGCTTGCCACTCTTGAGCGGTACAAGCTCCGCTTGGACGAGGTGGCCGGGACGCTCTC
CGCGCTCGAGATCGAGGATCTCGTGACCGTGCGGGATGTGACCGCGGTCGCGCAGCGGCTGGAGATGGTGCGGCGCATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTCGGGACGGATGGCCGACTGCTCGCCCTTCAGCTCGACGAGTTGATCGCC
GGGGTGGAGCCCGAGCGGGAGCTCGTCGTTCGGGACTATGTGCCCGAACCTACGGCCAAGCGGTCCCGGACCGTCGACGA
GGCGCTGTTCGAGCTCGACGCGCTGACACATGCCGAGCTTCTCGAACTGCCCACTGTGGCACGCGCGTTGGGGTACACCG
GGTCTCCGGAGACCCTGGACTCGGCCGTTTCGCCTCGCGGGTTCCGGCTGTTGGCGAAGGTGCCTCGGCTGCCCGGGGCC
ATCATCGACCGGCTTGTCGAGCACTTCGGGGGGCTGCAGAAGCTGCTCGCCGCCAGCGTCGATGATCTGCAGGCCGTGGA
CGGCGTCGGGGAGGCCCGTGCCCGGAGCGTGCGGGAAGGGCTCTCGCGGTTGGCCGAGTCGTCGATCCTGGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	44.598	96.524	0.43