Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG386_RS21220 Genome accession   NZ_CP108067
Coordinates   4881212..4881883 (+) Length   223 a.a.
NCBI ID   WP_030383691.1    Uniprot ID   A0A0L8N5J7
Organism   Streptomyces sp. NBC_00273     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4876212..4886883
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG386_RS21195 (OG386_21200) - 4876391..4876780 (+) 390 WP_030010939.1 nuclear transport factor 2 family protein -
  OG386_RS21200 (OG386_21205) - 4876786..4877427 (+) 642 WP_328789456.1 LysE family translocator -
  OG386_RS21205 (OG386_21210) - 4877635..4878678 (+) 1044 WP_328789457.1 alpha/beta hydrolase -
  OG386_RS21210 (OG386_21215) - 4878671..4879873 (+) 1203 WP_328789458.1 acyltransferase -
  OG386_RS21215 (OG386_21220) - 4879896..4881215 (+) 1320 WP_328789459.1 sensor histidine kinase -
  OG386_RS21220 (OG386_21225) vraR 4881212..4881883 (+) 672 WP_030383691.1 response regulator transcription factor Regulator
  OG386_RS21225 (OG386_21230) - 4881973..4883310 (+) 1338 WP_328789460.1 histidine kinase -
  OG386_RS21230 (OG386_21235) vraR 4883307..4883966 (+) 660 WP_327384073.1 response regulator transcription factor Regulator
  OG386_RS21235 (OG386_21240) - 4883996..4885204 (+) 1209 WP_328789461.1 cytochrome P450 -
  OG386_RS21240 (OG386_21245) - 4885201..4886811 (-) 1611 WP_328789462.1 ABC transporter permease -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 23812.54 Da        Isoelectric Point: 4.6064

>NTDB_id=652480 OG386_RS21220 WP_030383691.1 4881212..4881883(+) (vraR) [Streptomyces sp. NBC_00273]
MSTPIKVMIADDQMMVRQGFTVLLNAQPDIEVVGQAVDGADAVAKVAELAPDVVLMDIRMPGMGGIEATSVITAVPDAAV
KVLVLTTFDLDEYVYEALRAGASGFLLKDASADQLAEAVRVVAAGEALLSPNITKRLITEFSRLGAPRAPSRARIEALTE
RETEVLSLIAQGLSNAEISEHLVLAEQTVKTHVSRILVKLGLRDRTQAAVFAYETGLIRPTGY

Nucleotide


Download         Length: 672 bp        

>NTDB_id=652480 OG386_RS21220 WP_030383691.1 4881212..4881883(+) (vraR) [Streptomyces sp. NBC_00273]
ATGAGCACGCCGATCAAGGTGATGATCGCCGACGACCAGATGATGGTCCGGCAGGGCTTCACCGTGCTTCTCAACGCGCA
GCCCGACATAGAGGTCGTGGGGCAGGCGGTGGACGGGGCGGACGCGGTGGCGAAGGTCGCGGAGCTGGCTCCGGACGTGG
TGCTGATGGACATCCGGATGCCGGGGATGGGCGGGATCGAGGCCACGTCCGTGATCACCGCGGTTCCGGACGCCGCGGTG
AAGGTGCTGGTGCTGACCACCTTCGATCTCGACGAGTACGTGTACGAGGCGCTGCGGGCCGGGGCCTCCGGGTTCCTGCT
CAAGGACGCGTCCGCCGACCAGCTCGCCGAGGCGGTGCGGGTGGTGGCGGCCGGCGAGGCGCTGCTCTCGCCGAACATCA
CGAAGCGGCTGATCACGGAGTTCTCCCGGCTGGGAGCTCCGCGCGCGCCGTCACGGGCCAGGATCGAGGCGCTGACCGAG
CGGGAGACGGAGGTGCTGTCGCTGATCGCCCAGGGCCTGTCGAACGCCGAGATCTCGGAGCACTTGGTGCTGGCCGAGCA
GACGGTGAAGACGCATGTGAGCCGGATCCTGGTGAAGCTGGGGCTGCGGGACCGTACGCAGGCCGCGGTGTTCGCGTACG
AGACGGGTCTGATCCGCCCGACGGGCTACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-120)

Bacterial regulatory proteins, luxR family (GerE)

(157-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0L8N5J7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.161

97.309

0.439
  degU Bacillus subtilis subsp. subtilis str. 168

42.291

100

0.43