Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG386_RS11110 Genome accession   NZ_CP108067
Coordinates   2653318..2653953 (+) Length   211 a.a.
NCBI ID   WP_327382438.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00273     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2648318..2658953
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG386_RS11090 (OG386_11080) - 2649213..2650016 (+) 804 WP_202198919.1 IclR family transcriptional regulator -
  OG386_RS11095 (OG386_11085) - 2650150..2650842 (-) 693 WP_328788000.1 ABC transporter ATP-binding protein -
  OG386_RS11100 (OG386_11090) - 2650839..2651927 (-) 1089 WP_328788001.1 ABC transporter permease -
  OG386_RS11105 (OG386_11095) - 2652062..2653321 (+) 1260 WP_328788002.1 sensor histidine kinase -
  OG386_RS11110 (OG386_11100) vraR 2653318..2653953 (+) 636 WP_327382438.1 response regulator transcription factor Regulator
  OG386_RS11115 (OG386_11105) - 2654063..2654536 (+) 474 WP_328788003.1 hypothetical protein -
  OG386_RS11120 (OG386_11110) - 2654640..2656127 (-) 1488 WP_328788004.1 PLP-dependent aminotransferase family protein -
  OG386_RS11125 (OG386_11115) - 2656216..2656404 (+) 189 WP_328788005.1 hypothetical protein -
  OG386_RS11130 (OG386_11120) - 2656365..2657000 (+) 636 WP_328788006.1 nucleotidyltransferase family protein -
  OG386_RS11135 (OG386_11125) aceB 2657253..2658872 (+) 1620 WP_328788007.1 malate synthase A -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 22173.60 Da        Isoelectric Point: 6.1106

>NTDB_id=652450 OG386_RS11110 WP_327382438.1 2653318..2653953(+) (vraR) [Streptomyces sp. NBC_00273]
MTIRLLLADDHPVVRAGLRAVLDTEPDFAVVAEAATAERAVELAAREPVDVVLMDLQFGPGPGMHGSEATALITARPGAP
RVLVLTTYDTDADILAAVEAGASGYLLKDAPPEELAAAVRTAAAGQSALAPAVALRLMDRMRTPAEALTKRELEVLQLVA
DGLSNQQISKKLFLSQATVKSHLVHVYAKLGVDSRTSAVAAAATRRLIRTP

Nucleotide


Download         Length: 636 bp        

>NTDB_id=652450 OG386_RS11110 WP_327382438.1 2653318..2653953(+) (vraR) [Streptomyces sp. NBC_00273]
GTGACCATCCGTCTCCTGCTCGCCGACGACCACCCCGTGGTCCGGGCCGGGCTGCGCGCGGTGCTGGACACCGAACCGGA
CTTCGCGGTGGTGGCCGAGGCGGCGACGGCGGAGCGGGCGGTGGAACTGGCCGCCCGTGAACCGGTGGACGTGGTGCTGA
TGGACCTCCAGTTCGGTCCCGGTCCCGGGATGCACGGCTCCGAGGCGACGGCCCTGATCACCGCCCGCCCCGGCGCGCCC
CGGGTGCTGGTGCTGACCACGTACGACACCGACGCGGACATCCTGGCGGCGGTGGAGGCGGGCGCCTCGGGCTACCTGCT
CAAGGACGCCCCGCCGGAGGAGCTCGCGGCGGCCGTCCGGACGGCCGCGGCGGGCCAGTCGGCGCTGGCCCCGGCGGTGG
CACTGCGCCTGATGGACCGGATGCGGACCCCGGCGGAGGCGCTGACGAAGCGGGAGCTGGAGGTGCTGCAACTGGTCGCG
GACGGCCTGTCGAACCAGCAGATCTCCAAGAAGCTCTTCCTCAGCCAGGCCACGGTCAAGTCCCACCTGGTGCACGTCTA
CGCCAAGCTCGGCGTCGACTCCCGCACCTCGGCGGTCGCAGCAGCCGCCACCCGCCGCCTGATCCGCACCCCGTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-201)

Response regulator receiver domain (Response_reg)

(6-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.736

100

0.379
  degU Bacillus subtilis subsp. subtilis str. 168

34.545

100

0.36