Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG960_RS10490 Genome accession   NZ_CP108059
Coordinates   2397913..2398554 (-) Length   213 a.a.
NCBI ID   WP_327693951.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00280     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2392913..2403554
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG960_RS10460 (OG960_10520) - 2393394..2393900 (+) 507 WP_327693945.1 HNH endonuclease -
  OG960_RS10465 (OG960_10525) - 2393989..2394939 (-) 951 WP_371659005.1 SPFH domain-containing protein -
  OG960_RS10470 (OG960_10530) - 2395088..2395519 (-) 432 WP_371659006.1 NfeD family protein -
  OG960_RS10475 (OG960_10535) - 2395629..2396420 (-) 792 WP_327693948.1 ABC transporter ATP-binding protein -
  OG960_RS10480 (OG960_10540) - 2396544..2397326 (+) 783 WP_371659007.1 hypothetical protein -
  OG960_RS10485 (OG960_10545) chpE 2397520..2397765 (-) 246 WP_371659008.1 chaplin ChpE -
  OG960_RS10490 (OG960_10550) vraR 2397913..2398554 (-) 642 WP_327693951.1 response regulator transcription factor Regulator
  OG960_RS10495 (OG960_10555) - 2398547..2399692 (-) 1146 WP_371659009.1 GAF domain-containing sensor histidine kinase -
  OG960_RS10500 (OG960_10560) - 2399878..2400573 (+) 696 WP_371659010.1 SDR family NAD(P)-dependent oxidoreductase -
  OG960_RS10505 (OG960_10565) - 2400570..2401616 (+) 1047 WP_371659011.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OG960_RS10510 (OG960_10570) - 2401958..2402680 (+) 723 WP_371659012.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23139.41 Da        Isoelectric Point: 5.3618

>NTDB_id=652355 OG960_RS10490 WP_327693951.1 2397913..2398554(-) (vraR) [Streptomyces sp. NBC_00280]
MADAIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEASDGAEGVDRAQELKPDVVLMDIKMPGMDGVEALRRLRELDNPAR
VLIVTSFTEQRTVVPALRAGAAGYVYKDIDPDALAGAIRSVHAGHILLQPEVAGALLSQEETHSGQGRSGSLTEREREVL
TLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGVTG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=652355 OG960_RS10490 WP_327693951.1 2397913..2398554(-) (vraR) [Streptomyces sp. NBC_00280]
GTGGCTGACGCGATCAAGGTGCTGCTCGTCGACGACCACCAAGTGGTCCGCCGGGGCCTGCGCACGTTCCTCGAAGTGCA
GGACGACATCGAGGTCGTGGGCGAGGCGTCGGACGGTGCCGAGGGAGTCGACCGCGCGCAGGAACTGAAACCCGACGTCG
TCCTCATGGACATCAAGATGCCGGGCATGGACGGCGTCGAGGCGTTGCGCAGACTCCGCGAACTCGACAACCCCGCGCGC
GTGCTGATCGTCACGAGCTTCACCGAGCAGCGCACGGTGGTCCCCGCACTGCGCGCGGGCGCCGCCGGGTACGTCTACAA
GGACATCGACCCGGACGCCCTCGCCGGCGCGATCCGCTCCGTGCACGCCGGACACATCCTGCTCCAGCCCGAGGTCGCGG
GCGCACTGCTGAGCCAGGAGGAGACGCACTCGGGCCAGGGGAGGAGCGGCTCGCTCACCGAGCGGGAGCGCGAGGTGCTG
ACCCTGATCGCGGACGGCCGCTCGAACCGGGAGATAGCCCGCGCCCTGGTGCTGTCCGAGAAGACGGTCAAGACGCATGT
CTCGAACATCCTGATGAAACTCGACCTGGCGGACCGTACGCAGGCGGCGTTGTGGGCGGTACGTCACGGTGTGACCGGAT
GA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.411

98.122

0.455
  degU Bacillus subtilis subsp. subtilis str. 168

39.367

100

0.408